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The incidence of postoperative nausea and vomiting after thyroidectomy using three anaesthetic techniques.

Authors
Won, YJ; Yoo, JY; Chae, YJ; Kim, DH; Park, SK; Cho, HB; Kim, JS; Lee, JH; Lee, SY
Citation
The Journal of international medical research, 39(5):1834-1842, 2011
Journal Title
The Journal of international medical research
ISSN
0300-06051473-2300
Abstract
The choice of anaesthetics can affect the incidence of postoperative nausea and vomiting (PONV). This study compared the incidence of PONV in 177 female patients who underwent thyroidectomy, with anaesthesia induced and maintained using one of three regimens: (i) sevoflurane (thiopental sodium 4 - 5 mg/kg and sevoflurane 2.0 - 2.5 vol% in 50% air); (ii) total intravenous anaesthesia (TIVA; propofol-remifentanil [target blood concentrations 2.5 - 3.5 μg/ml and 3.5 - 4.5 ng/ml, respectively]); or (iii) combined inhalation and intravenous anaesthesia (sevoflurane 1.0 vol% in 50% air plus propofol-remifentanil [target blood concentrations 1.5 - 2.5 μg/ml and 2.5 - 3.5 ng/ml, respectively]). The incidence and severity of PONV and the need for rescue antiemetics were assessed at 0 - 24 h postoperatively. Overall, the incidence of PONV was significantly lower in the TIVA and combined groups compared with the sevoflurane group (33.9%, 39.0% and 64.4%, respectively). In conclusion, the maintenance of anaesthesia with propofol-remifentanil or sevoflurane-propofol-remifentanil decreased the incidence of PONV compared with sevoflurane alone.
MeSH terms
Adult*Anesthetics, Combined*Anesthetics, Inhalation*Anesthetics, IntravenousFemaleHumansIncidenceMethyl EthersMiddle AgedPiperidinesPostoperative Nausea and Vomiting/epidemiology/*prevention & controlPropofol*ThyroidectomyTreatment Outcome
DOI
10.1177/147323001103900526
PMID
22117984
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Anesthesiology & Pain Medicine
AJOU Authors
채, 윤정김, 대희박, 선경조, 한범김, 진수이, 숙영
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