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Effect of zoledronic acid on acro-osteolysis and osteoporosis in a patient with Hajdu-Cheney syndrome.

Authors
Hwang, S; Shin, DY; Moon, SH; Lee, EJ; Lim, SK; Kim, OH; Rhee, Y
Citation
Yonsei medical journal, 52(3):543-546, 2011
Journal Title
Yonsei medical journal
ISSN
0513-57961976-2437
Abstract
Hajdu-Cheney syndrome is a rare, autosomal dominant skeletal dysplasia marked by acro-osteolysis of the distal phalanges and severe osteoporosis. Although there are more than 60 reports published to date, proper treatment and subsequent outcome have been scarce. Herein, we report a progress of anti-resorptive therapy with zoledronic acid, in a woman with Hajdu-Cheney syndrome. Results suggest that anti-resorptive therapy may be important in delaying the progress of osteoporosis and preventing fractures, but not necessarily acro-osteolysis itself.
MeSH terms
Acro-Osteolysis/complications/*drug therapyAdultBone Density Conservation Agents/*therapeutic useDiphosphonates/*therapeutic useFemaleHajdu-Cheney Syndrome/complications/*drug therapyHumansImidazoles/*therapeutic useOsteoporosis/complications/*drug therapy
DOI
10.3349/ymj.2011.52.3.543
PMID
21488202
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Radiology
AJOU Authors
김, 옥화
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