Parotid gland as a risk organ in whole brain radiotherapy.
Noh, OK; Chun, M; Nam, SS; Jang, H; Jo, S; Oh, YT; Lim, JC
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 98(2):223-226, 2011
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: Since the introduction of CT-based simulation for use in whole brain radiotherapy (WBRT), we have observed that a large volume of the parotid glands is included in the radiation fields. The purpose of this study is to analyze the dose-volume statistics of the parotid glands in patients undergoing WBRT.
MATERIALS AND METHODS: Thirty-two patients received WBRT using CT-based simulation with bilateral two-field arrangement. Daily fraction was 3 Gy with total dose of 30 Gy in 2 weeks. We analyzed the radiation dose from WBRT to the parotid glands.
RESULTS: Average of the mean parotid dose was 17.5 Gy (range, 10.5-26.2) for both glands. Mean parotid doses ≥20 and ≥25 Gy were observed in 22 (34.4%) and 4 (6.3%) of 64 individual glands. The numbers of patients with a mean parotid dose of both glands ≥20Gy and ≥25 Gy were 12 (37.5%) and 1 (3.1%), respectively.
CONCLUSIONS: Mean parotid dose was variable in patients with WBRT. According to the parotid dose and combined potential risk factors, parotid glands can be regarded as a risk organ in WBRT for improvement of patient quality of life.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
Total Visit :2,779,772
Total Download :1,134,074
Today View :2,417
Ajou University Medical Information & Media Center 164 Worldcup-ro Yeongtong-gu Suwon 16499 Korea / TEL : 031-219-5312 / FAX : 031-219-5314 Copyright (c) Ajou University Medical Information & Media Center All Rights Reserved. AJOU Open Repository는 국립중앙도서관 OAK 보급사업으로 구축되었습니다.