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Clinical features and survival outcomes in patients with multiple myeloma: analysis of web-based data from the Korean Myeloma Registry.

Authors
Kim, SJ; Kim, K; Kim, BS; Jo, DY; Kang, HJ; Kim, JS; Mun, YC; Kim, CS; Sohn, SK; Eom, HS; Kwak, JY; Shim, H; Yoon, HJ; Jin, JY; Min, CK; Shin, H; Won, JH; Lee, JJ; Kwon, JH; Joo, YD; Do, YR; Kim, SH; Oh, S; Suh, C; Lee, J; Yoon, SS; Kim, MK; Bang, SM; Ryoo, HM; Kim, H; Kim, HJ; Kim, YS; Park, CW; Lee, GW; Shin, HJ; Park, SK; Park, JS; Kim, HY; Lee, DS; Lee, JH; Korean Multiple Myeloma Working Party
Citation
Acta haematologica, 122(4):200-210, 2009
Journal Title
Acta haematologica
ISSN
0001-57921421-9662
Abstract
AIM: The Korean Multiple Myeloma Working Party performed a nationwide registration of multiple myeloma patients via a web-based data bank system. METHODS: We retrospectively analyzed registered data from 3,209 patients since 1999. RESULTS: The median overall survival (OS) was 50.13 months (95% confidence interval: 46.20-54.06 months). Patients < or =40 years demonstrated a longer OS than patients >65 years of age (median OS 71.13 vs. 36.73 months, p < 0.001). Patients who received novel agents at any time during their treatments showed a longer OS than patients who did not (median OS 42.23 vs. 55.50 months, p < 0.001). Response to treatment was associated with OS, with tandem autologous stem cell transplantation (SCT) producing longer OS than single autologous SCT. CONCLUSIONS: We demonstrated associations between survival outcomes and treatment modalities as well as baseline disease characteristics in a registry of multiple myeloma patients using a web-based data analysis.
MeSH terms
AdultAgedAged, 80 and overChromosome AberrationsFemaleHumansInternetKaplan-Meier EstimateMaleMiddle AgedMultiple Myeloma/diagnosisMultiple Myeloma/geneticsMultiple Myeloma/mortality*Multiple Myeloma/therapyPrognosisRegistries/statistics & numerical dataRepublic of Korea/epidemiologyStem Cell TransplantationTransplantation, AutologousTransplantation, HomologousYoung Adult
DOI
10.1159/000253027
PMID
19887776
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Hematology-Oncology
AJOU Authors
박준성
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