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Nanostructured films as a novel substrate for chondrocytes growth.

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dc.contributor.authorKim, HS-
dc.contributor.authorChoi, WH-
dc.contributor.authorSong, YA-
dc.contributor.authorLee, HJ-
dc.contributor.authorMin, BH-
dc.contributor.authorKim, JH-
dc.date.accessioned2012-05-09T05:27:08Z-
dc.date.available2012-05-09T05:27:08Z-
dc.date.issued2011-
dc.identifier.issn1533-4880-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/6880-
dc.description.abstractWe fabricated a large area silica nano-particle monolayer on glass substrates for the cell growth by the Langmuir-Blodgett technique. A thin film of 300 nm sized mono-dispersed silica particles was constructed on the air-water interface and transferred onto a glass substrate. Chondrocytes were cultured on nano-structured substrates and bare glass substrates for 8 days. The characterizations of chondrocytes on nano-structured substrate were conducted on 3rd and 6th day using confocal laser microscopy and with MTT assay for 8 days. The chondrocytes cultured on nano-structured substrate showed podia like spike and their size was larger than that formed on bare glass substrate. The metabolic activity of chondrocytes on nano-structured substrate was lower than that on bare glass substrate at early-stage, but it was recovered after 4 days.-
dc.language.isoen-
dc.subject.MESHCell Division-
dc.subject.MESHCells, Cultured-
dc.subject.MESHChondrocytes-
dc.subject.MESHHumans-
dc.subject.MESHMicroscopy, Atomic Force-
dc.subject.MESHMicroscopy, Confocal-
dc.subject.MESHMicroscopy, Electron, Scanning-
dc.subject.MESHNanostructures-
dc.titleNanostructured films as a novel substrate for chondrocytes growth.-
dc.typeArticle-
dc.identifier.pmid21780439-
dc.contributor.affiliatedAuthor민, 병현-
dc.type.localJournal Papers-
dc.citation.titleJournal of nanoscience and nanotechnology-
dc.citation.volume11-
dc.citation.number5-
dc.citation.date2011-
dc.citation.startPage4265-
dc.citation.endPage4268-
dc.identifier.bibliographicCitationJournal of nanoscience and nanotechnology, 11(5). : 4265-4268, 2011-
dc.identifier.eissn1533-4899-
dc.relation.journalidJ015334880-
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Journal Papers > School of Medicine / Graduate School of Medicine > Orthopedic Surgery
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