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Physiological evaluation of the provisional side-branch intervention strategy for bifurcation lesions using fractional flow reserve.

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dc.contributor.authorKoo, BK-
dc.contributor.authorPark, KW-
dc.contributor.authorKang, HJ-
dc.contributor.authorCho, YS-
dc.contributor.authorChung, WY-
dc.contributor.authorYoun, TJ-
dc.contributor.authorChae, IH-
dc.contributor.authorChoi, DJ-
dc.contributor.authorTahk, SJ-
dc.contributor.authorOh, BH-
dc.contributor.authorPark, YB-
dc.contributor.authorKim, HS-
dc.date.accessioned2010-12-21T05:49:25Z-
dc.date.available2010-12-21T05:49:25Z-
dc.date.issued2008-
dc.identifier.issn0195-668X-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/733-
dc.description.abstractAIMS: This study was performed to evaluate the functional outcomes of fractional flow reserve (FFR)-guided jailed side-branch (SB) intervention strategy.



METHODS AND RESULTS: One hundred and ten patients treated by provisional strategy were consecutively enrolled and SB FFR was measured in 91 patients. SB intervention was allowed when FFR was <0.75. FFR measurement was repeated after SB intervention and at 6-month follow-up angiography. In 26 of 28 SB lesions with FFR <0.75, balloon angioplasty (SB balloon/artery ratio = 0.84 +/- 0.14) was performed and FFR >or=0.75 was achieved in 92% of the lesions although the mean residual stenosis was 69 +/- 10%. During follow-up, there were no changes in SB FFR in lesions with (0.86 +/- 0.05 to 0.84 +/- 0.01, P = 0.4) and without SB angioplasty (0.87 +/- 0.06 to 0.89 +/- 0.07, P = 0.1). Functional restenosis (FFR <0.75) rate was only 8% (5/65). When clinical outcomes of these patients were compared with 110 patients with similar bifurcation lesions treated without FFR-guidance, there was no difference in 9-month cardiac event rates (4.6 vs. 3.7%, P = 0.7) between the two groups.



CONCLUSION: In conclusion, FFR-guided SB intervention strategy resulted in good functional outcomes.
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dc.language.isoen-
dc.subject.MESHBalloon Dilation-
dc.subject.MESHCoronary Stenosis-
dc.subject.MESHDeath, Sudden, Cardiac-
dc.subject.MESHDrug-Eluting Stents-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHFractional Flow Reserve, Myocardial-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMyocardial Infarction-
dc.subject.MESHMyocardial Revascularization-
dc.subject.MESHTreatment Outcome-
dc.titlePhysiological evaluation of the provisional side-branch intervention strategy for bifurcation lesions using fractional flow reserve.-
dc.typeArticle-
dc.identifier.pmid18308689-
dc.identifier.urlhttp://eurheartj.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=18308689-
dc.contributor.affiliatedAuthor탁, 승제-
dc.type.localJournal Papers-
dc.identifier.doi10.1093/eurheartj/ehn045-
dc.citation.titleEuropean heart journal-
dc.citation.volume29-
dc.citation.number6-
dc.citation.date2008-
dc.citation.startPage726-
dc.citation.endPage732-
dc.identifier.bibliographicCitationEuropean heart journal, 29(6). : 726-732, 2008-
dc.identifier.eissn1522-9645-
dc.relation.journalidJ00195668X-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
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