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Prognostic value of longitudinal strain after primary reperfusion therapy in patients with anterior-wall acute myocardial infarction.

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dc.contributor.authorPark, YH-
dc.contributor.authorKang, SJ-
dc.contributor.authorSong, JK-
dc.contributor.authorLee, EY-
dc.contributor.authorSong, JM-
dc.contributor.authorKang, DH-
dc.contributor.authorKim, YH-
dc.contributor.authorLee, CW-
dc.contributor.authorHong, MK-
dc.contributor.authorKim, JJ-
dc.contributor.authorPark, SW-
dc.contributor.authorPark, SJ-
dc.date.accessioned2010-12-21T06:54:30Z-
dc.date.available2010-12-21T06:54:30Z-
dc.date.issued2008-
dc.identifier.issn0894-7317-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/736-
dc.description.abstractOBJECTIVES: We sought to test whether longitudinal strain (LS) can be a useful predictor of left ventricular (LV) remodeling after reperfusion therapy in acute myocardial infarction.



BACKGROUND: Predicting LV remodeling based on quantification of regional contractility remains an elusive goal of echocardiography.



METHODS: In 50 patients with anterior-wall acute myocardial infarction, the peak systolic velocity and LS were measured by Doppler tissue imaging (LS(DTI)) and speckle tracking imaging (LS(2D)) at 7 LV segments of left anterior descending coronary artery territory after primary reperfusion therapy. LV remodeling was defined as an increase in LV end-diastolic volume of greater than or equal to 15% at follow-up echocardiography.



RESULTS: A total of 22 patients showed LV remodeling, who had significantly lower baseline ejection fraction, LS(DTI), and LS(2D), and higher wall-motion score index and peak creatine kinase-MB with shorter deceleration time of early diastolic mitral inflow than those without LV remodeling. LS(2D) (odds ratio [OR] = 1.307, 95% confidence interval [CI] = 1.082-1.579, P = .005) and LS(DTI) (OR = 1.430, 95% CI = 1.152-1.776, P = .001) were independent predictors of LV remodeling. During clinical follow-up of 18.3 +/- 9.0 months, death or congestive heart failure developed in 11 patients (22%); LS(2D) (OR = 1.455, 95% CI = 1.142-1.852, P = .002) and LS(DTI) (OR = 1.436, 95% CI = 1.093-1.888, P = .009) were independent predictors.



CONCLUSIONS: LS immediately after primary reperfusion therapy is an excellent predictor of LV remodeling and adverse events in patients with anterior-wall acute myocardial infarction.
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dc.language.isoen-
dc.subject.MESHEchocardiography-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMyocardial Infarction-
dc.subject.MESHMyocardial Reperfusion-
dc.subject.MESHPrognosis-
dc.subject.MESHReproducibility of Results-
dc.subject.MESHSensitivity and Specificity-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHVentricular Dysfunction, Left-
dc.titlePrognostic value of longitudinal strain after primary reperfusion therapy in patients with anterior-wall acute myocardial infarction.-
dc.typeArticle-
dc.identifier.pmid17904803-
dc.identifier.urlhttp://linkinghub.elsevier.com/retrieve/pii/S0894-7317(07)00594-9-
dc.contributor.affiliatedAuthor강, 수진-
dc.type.localJournal Papers-
dc.identifier.doi10.1016/j.echo.2007.08.026-
dc.citation.titleJournal of the American Society of Echocardiography-
dc.citation.volume21-
dc.citation.number3-
dc.citation.date2008-
dc.citation.startPage262-
dc.citation.endPage267-
dc.identifier.bibliographicCitationJournal of the American Society of Echocardiography, 21(3). : 262-267, 2008-
dc.identifier.eissn1097-6795-
dc.relation.journalidJ008947317-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
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