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Comparison of accuracy in the prediction of left ventricular wall motion changes between invasively assessed microvascular integrity indexes and fluorine-18 fluorodeoxyglucose positron emission tomography in patients with ST-elevation myocardial infarction.

Authors
Yoon, MH; Tahk, SJ; Yang, HM; Woo, SI; Lim, HS; Kang, SJ; Choi, BJ; Choi, SY; Hwang, GS; Shin, JH
Citation
The American journal of cardiology, 102(2):129-134, 2008
Journal Title
The American journal of cardiology
ISSN
0002-91491879-1913
Abstract
We compared the accuracy in predicting regional wall motion score index (RWMSI) changes between microvascular integrity indexes measured during primary percutaneous coronary intervention (PCI) and fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) in ST-elevation myocardial infarction (STEMI). Fifty patients with STEMI were enrolled. Microvascular integrity indexes were measured using an intracoronary Doppler wire and a pressure wire after primary PCI. We performed FDG-PET 7 days after PCI. RWMSI on follow-up echocardiogram (5.8 +/- 1.7 months) revealed good correlations with coronary flow reserve (r = -0.442, p = 0.002), diastolic deceleration time (r = -0.511, p <0.001), microvascular resistance index (r = 0.443, p = 0.002), coronary wedge pressure (r = 0.474, p <0.001), and FDG uptake rate (r = -0.571, p <0.001). There were no significant differences in areas under the curve for predicting RWMSI changes between microvascular integrity indexes and FDG-PET (coronary flow reserve 0.696, diastolic deceleration time 0.731, microvascular resistance index 0.748, coronary wedge pressure 0.694, Thrombolysis In Myocardial Infarction myocardial perfusion grade 0.702, and FDG-PET 0.755). In conclusion, microvascular integrity indexes assessed during primary PCI are useful and comparable to FDG-PET in predicting left ventricular functional changes in STEMI.
MeSH terms
Angioplasty, Balloon, CoronaryFemaleFluorodeoxyglucose F18/diagnostic use*Health Status IndicatorsHeart Conduction System/physiopathology*Heart Function TestsHeart Ventricles/physiopathology*HumansMaleMiddle AgedMyocardial Infarction/diagnosisMyocardial Infarction/physiopathology*Myocardial Infarction/therapyMyocardial Infarction/ultrasonographyPositron-Emission Tomography*/methodsROC CurveRadiopharmaceuticals/diagnostic use
DOI
10.1016/j.amjcard.2008.03.024
PMID
18602508
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
AJOU Authors
윤, 명호탁, 승제양, 형모임, 홍석강, 수진최, 병주최, 소연황, 교승신, 준한
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