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Comparison of accuracy in the prediction of left ventricular wall motion changes between invasively assessed microvascular integrity indexes and fluorine-18 fluorodeoxyglucose positron emission tomography in patients with ST-elevation myocardial infarction.

Yoon, MH; Tahk, SJ; Yang, HM; Woo, SI; Lim, HS; Kang, SJ; Choi, BJ; Choi, SY; Hwang, GS; Shin, JH
The American journal of cardiology, 102(2):129-134, 2008
Journal Title
The American journal of cardiology
We compared the accuracy in predicting regional wall motion score index (RWMSI) changes between microvascular integrity indexes measured during primary percutaneous coronary intervention (PCI) and fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) in ST-elevation myocardial infarction (STEMI). Fifty patients with STEMI were enrolled. Microvascular integrity indexes were measured using an intracoronary Doppler wire and a pressure wire after primary PCI. We performed FDG-PET 7 days after PCI. RWMSI on follow-up echocardiogram (5.8 +/- 1.7 months) revealed good correlations with coronary flow reserve (r = -0.442, p = 0.002), diastolic deceleration time (r = -0.511, p <0.001), microvascular resistance index (r = 0.443, p = 0.002), coronary wedge pressure (r = 0.474, p <0.001), and FDG uptake rate (r = -0.571, p <0.001). There were no significant differences in areas under the curve for predicting RWMSI changes between microvascular integrity indexes and FDG-PET (coronary flow reserve 0.696, diastolic deceleration time 0.731, microvascular resistance index 0.748, coronary wedge pressure 0.694, Thrombolysis In Myocardial Infarction myocardial perfusion grade 0.702, and FDG-PET 0.755). In conclusion, microvascular integrity indexes assessed during primary PCI are useful and comparable to FDG-PET in predicting left ventricular functional changes in STEMI.
MeSH terms
Angioplasty, Balloon, CoronaryFemaleFluorodeoxyglucose F18/diagnostic use*Health Status IndicatorsHeart Conduction System/physiopathology*Heart Function TestsHeart Ventricles/physiopathology*HumansMaleMiddle AgedMyocardial Infarction/diagnosisMyocardial Infarction/physiopathology*Myocardial Infarction/therapyMyocardial Infarction/ultrasonographyPositron-Emission Tomography*/methodsROC CurveRadiopharmaceuticals/diagnostic use
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Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
AJOU Authors
윤, 명호탁, 승제양, 형모임, 홍석강, 수진최, 병주최, 소연황, 교승신, 준한
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