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Usefulness of minimum stent cross sectional area as a predictor of angiographic restenosis after primary percutaneous coronary intervention in acute myocardial infarction (from the HORIZONS-AMI Trial IVUS substudy)
DC Field | Value | Language |
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dc.contributor.author | Choi, SY | - |
dc.contributor.author | Maehara, A | - |
dc.contributor.author | Cristea, E | - |
dc.contributor.author | Witzenbichler, B | - |
dc.contributor.author | Guagliumi, G | - |
dc.contributor.author | Brodie, B | - |
dc.contributor.author | Kellett, MA Jr | - |
dc.contributor.author | Dressler, O | - |
dc.contributor.author | Lansky, AJ | - |
dc.contributor.author | Parise, H | - |
dc.contributor.author | Mehran, R | - |
dc.contributor.author | Mintz, GS | - |
dc.contributor.author | Stone, GW | - |
dc.date.accessioned | 2013-04-22T05:12:30Z | - |
dc.date.available | 2013-04-22T05:12:30Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0002-9149 | - |
dc.identifier.uri | http://repository.ajou.ac.kr/handle/201003/7788 | - |
dc.description.abstract | HORIZONS-AMI was a prospective dual-arm randomized trial of different antithrombotic regimens and stent types in patients with ST-segment elevation myocardial infarction. A formal intravascular ultrasound (IVUS) substudy enrolled 464 patients with baseline and 13-month follow-up at 36 centers. Of them, 318 patients with 355 lesions were evaluated for this study. Angiographic restenosis occurred in 45 of 355 lesions (12.7%). Bare-metal stent use (45.5% vs 21.2%, p <0.001) and diabetes mellitus (29.5% vs 10.9%, p <0.001) were more prevalent in patients with versus without restenosis. Postprocedure IVUS minimum lumen area (5.6 mm(2), 5.0 to 6.1, vs 6.7 mm(2), 6.5 to 6.9, p <0.001), minimum stent area (5.7 mm(2), 5.1 to 6.3, vs 6.9 mm(2), 6.6 to 7.1, p <0.001), and reference average lumen area (7.7 mm(2), 6.8 to 8.6, vs 9.7 mm(2), 9.3 to 10.1, p <0.001) were smaller in restenotic versus nonrestenotic lesions. By multivariable analysis, minimum stent area was an independent predictor of angiographic restenosis (odds ratio 0.75, 95% confidence interval 0.61 to 0.93, p = 0.009) in addition to diabetes, bare-metal stent use, and longer stent length. Attenuated plaque behind the stent struts had a trend to predict less binary restenosis (p = 0.07). In conclusion, a smaller IVUS minimum stent area was an independent predictor of angiographic restenosis after primary percutaneous intervention in patients with ST-segment elevation myocardial infarction, similar to patients with stable coronary artery disease. | - |
dc.language.iso | en | - |
dc.subject.MESH | Angioplasty, Balloon, Coronary | - |
dc.subject.MESH | Coronary Angiography | - |
dc.subject.MESH | Coronary Restenosis | - |
dc.subject.MESH | Coronary Vessels | - |
dc.subject.MESH | Diabetes Mellitus | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Multivariate Analysis | - |
dc.subject.MESH | Myocardial Infarction | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Prosthesis Design | - |
dc.subject.MESH | Stents | - |
dc.subject.MESH | Ultrasonography, Interventional | - |
dc.title | Usefulness of minimum stent cross sectional area as a predictor of angiographic restenosis after primary percutaneous coronary intervention in acute myocardial infarction (from the HORIZONS-AMI Trial IVUS substudy) | - |
dc.type | Article | - |
dc.identifier.pmid | 22118823 | - |
dc.identifier.url | http://linkinghub.elsevier.com/retrieve/pii/S0002-9149(11)03032-3 | - |
dc.contributor.affiliatedAuthor | 최, 소연 | - |
dc.type.local | Journal Papers | - |
dc.identifier.doi | 10.1016/j.amjcard.2011.10.005 | - |
dc.citation.title | The American journal of cardiology | - |
dc.citation.volume | 109 | - |
dc.citation.number | 4 | - |
dc.citation.date | 2012 | - |
dc.citation.startPage | 455 | - |
dc.citation.endPage | 460 | - |
dc.identifier.bibliographicCitation | The American journal of cardiology, 109(4). : 455-460, 2012 | - |
dc.identifier.eissn | 1879-1913 | - |
dc.relation.journalid | J000029149 | - |
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