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Final kissing ballooning and long-term clinical outcomes in coronary bifurcation lesions treated with 1-stent technique: results from the COBIS registry

DC Field Value Language
dc.contributor.authorGwon, HC-
dc.contributor.authorHahn, JY-
dc.contributor.authorKoo, BK-
dc.contributor.authorSong, YB-
dc.contributor.authorChoi, SH-
dc.contributor.authorChoi, JH-
dc.contributor.authorLee, SH-
dc.contributor.authorJeong, MH-
dc.contributor.authorKim, HS-
dc.contributor.authorSeong, IW-
dc.contributor.authorYang, JY-
dc.contributor.authorRha, SW-
dc.contributor.authorJang, Y-
dc.contributor.authorYoon, JH-
dc.contributor.authorTahk, SJ-
dc.contributor.authorSeung, KB-
dc.contributor.authorPark, SJ-
dc.date.accessioned2013-04-22T05:32:22Z-
dc.date.available2013-04-22T05:32:22Z-
dc.date.issued2012-
dc.identifier.issn1355-6037-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/7791-
dc.description.abstractBACKGROUND: Whether final kissing ballooning (FKB) is mandatory in the 1-stent technique is uncertain.



OBJECTIVE: To evaluate the effect of FKB on long-term clinical outcomes in coronary bifurcation lesions treated with the 1-stent technique.



METHODS: Consecutive patients undergoing percutaneous coronary intervention using drug-eluting stents for non-left main bifurcation lesions were enrolled from 16 centres in Korea between January 2004 and June 2006. In patients treated with the 1-stent technique major adverse cardiac events (MACE; cardiac death, myocardial infarction (MI), or target lesion revascularisation (TLR)) were compared between those undergoing main vessel stenting only (non-FKB group, n=736) or those undergoing FKB after main vessel stenting (FKB group, n=329). Propensity score-matching analysis was also performed in 222 patient pairs (444 from the non-FKB group and 222 from the FKB group).



RESULTS: During follow-up (median 22 months), the FKB group had a higher incidence of MACE (HR 2.58; 95% CI 1.52 to 4.37; p<0.001) and TLR (HR 3.63; 95% CI 2.00 to 6.56; p<0.001), but not of cardiac death or MI. Most TLR occurred in the main vessel (HR 3.39 for the FKB group; 95% CI 1.86 to 6.19; p<0.001). The rate of stent thrombosis was similar in both groups (0.5% in the non-FKB group vs 0.6% in the FKB group, p=0.99). After propensity score matching, the FKB group still had higher rates of MACE and TLR than the non-FKB group (HR 2.13; 95% CI 1.15 to 3.95; p=0.02 and HR 2.84; 95% CI 1.45 to 5.55; p=0.002, respectively).



CONCLUSIONS: In patients treated with the 1-stent technique for bifurcation lesions, FKB after main vessel stenting may be harmful mainly due to increased TLR.



TRIAL REGISTRATION NUMBER: clinicaltrials.gov number: NCT00851526.
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dc.language.isoen-
dc.subject.MESHAngioplasty, Balloon, Coronary/*instrumentation-
dc.subject.MESHCause of Death-
dc.subject.MESHCoronary Angiography-
dc.subject.MESHCoronary Stenosis/mortality/radiography/*surgery-
dc.subject.MESHElectrocardiography-
dc.subject.MESHEquipment Design-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHIncidence-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPostoperative Complications/epidemiology-
dc.subject.MESHPropensity Score-
dc.subject.MESHProsthesis Design-
dc.subject.MESH*Registries-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESH*Stents-
dc.subject.MESHSurvival Rate/trends-
dc.subject.MESHTime Factors-
dc.subject.MESHTreatment Outcome-
dc.titleFinal kissing ballooning and long-term clinical outcomes in coronary bifurcation lesions treated with 1-stent technique: results from the COBIS registry-
dc.typeArticle-
dc.identifier.pmid21933939-
dc.identifier.urlhttp://heart.bmj.com/cgi/pmidlookup?view=long&pmid=21933939-
dc.contributor.affiliatedAuthor탁, 승제-
dc.type.localJournal Papers-
dc.identifier.doi10.1136/heartjnl-2011-300322-
dc.citation.titleHeart (British Cardiac Society)-
dc.citation.volume98-
dc.citation.number3-
dc.citation.date2012-
dc.citation.startPage225-
dc.citation.endPage231-
dc.identifier.bibliographicCitationHeart (British Cardiac Society), 98(3):225-231, 2012-
dc.identifier.eissn1468-201X-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
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