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Acquired hemophilia successfully treated with activated prothrombin complex concentrate and immunosuppressant combination: a case report

Authors
Kang, E; Kim, HG; Lee, JH; Lee, M; Bae, CB; Jeon, JY; Ahn, MS; Jeong, SH; Park, JS; Kang, SY; Choi, JH; Lee, HW
Citation
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 23(7):669-672, 2012
Journal Title
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
ISSN
0957-52351473-5733
Abstract
Acquired hemophilia A is a very rare but life-threatening disorder caused by autoantibody against coagulation factor VIII. The incidence was much rarer in young people. In this case report, a young woman presented with spontaneous muscle hematoma. Because of pain and limited range of motion, she underwent surgery for resolution at first. However, her symptoms and hemorrhage worsened. She was diagnosed with acquired hemophilia A. We started combination treatment with bypassing agent, activated prothrombin complex and immunosuppressants immediately and the results were successful. The acute bleeding was controlled and autoantibody was completely resolved.
DOI
10.1097/MBC.0b013e32835669e6
PMID
22918088
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Hematology-Oncology
AJOU Authors
안, 미선정, 성현박, 준성강, 석윤최, 진혁이, 현우
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