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Construction of an open-access QT database for detecting the proarrhythmia potential of marketed drugs: ECG-ViEW

Authors
Park, MY; Yoon, D; Choi, NK; Lee, J; Lee, K; Lim, HS; Park, BJ; Kim, JH; Park, RW
Citation
Clinical pharmacology and therapeutics, 92(3):393-396, 2012
Journal Title
Clinical pharmacology and therapeutics
ISSN
0009-92361532-6535
Abstract
Information about the QT interval from surface electrocardiograms (ECGs) is essential for surveillance of the proarrhythmia potential of marketed drugs. However, ECG records obtained in daily practice cannot be easily used for this purpose without labor-intensive manual effort. This study was aimed at constructing an open-access QT database, the Electrocardiogram Vigilance with Electronic Data Warehouse (ECG-ViEW). This longitudinal observational database contains 710,369 measurements of QT and associated clinical data from 371,401 patients. The de-identified database is freely available at http://www.ecgview.org.
MeSH terms
*Access to InformationAdolescentAdultAgedAged, 80 and overArrhythmias, Cardiac/*chemically inducedChildChild, Preschool*Databases, FactualElectrocardiography/*drug effectsFemaleHumansInfantInfant, NewbornMaleMiddle AgedPharmaceutical Preparations/*adverse effectsYoung Adult
DOI
10.1038/clpt.2012.93
PMID
22828716
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Medical Informatics
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
AJOU Authors
박, 만영이, 기영임, 홍석박, 래웅
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