Successful treatment of chronic eosinophilic pneumonia with anti-IgE therapy
Shin, YS; Jin, HJ; Yoo, HS; Hwang, EK; Nam, YH; Ye, YM; Park, HS
Journal of Korean medical science, 27(10):1261-1264, 2012
Journal of Korean medical science
Anti-IgE therapy, using recombinant humanized anti-IgE antibodies, is clinically effective in patients with eosinophil-related disorders such as allergic asthma, allergic rhinitis, and chronic urticaria. Chronic eosinophilic pneumonia tends to respond promptly to systemic corticosteroid therapy, however; relapses are common following corticosteroid tapering. We treated two patients (17- and 19-yr-old males) of chronic eosinophilic pneumonia whose symptoms were cough and dyspnea on exertion. The symptoms were recurrent while tapering off corticosteroid. They were treated with anti-IgE antibody without recurrence for 2 yr and 15 months. Here, we first describe clinical experience of the 2 cases of chronic eosinophilic pneumonia.
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