Learning from HSV-infected mice as a model of Behçet's disease
Sohn, S; Lee, ES; Bang, D
Clinical and experimental rheumatology, 30(3 Suppl 72):S96-103, 2012
Clinical and experimental rheumatology
Several animal models of Behçet's disease (BD) have been proposed according to putative etiology. Among these models, the herpes simplex virus (HSV)-induced model produced the most similar disease attributes observe in patients. Inoculation of HSV type 1 to the scratched earlobe of mice produced the appropriate symptoms, including oral, genital, and skin ulcers, eye lesions, arthritis, and intestinal involvement. This HSV-induced BD model is the only continuously used model, to which various therapeutic modalities have been applied.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
Total Visit :3,086,648
Total Download :1,259,496
Today View :733
Ajou University Medical Information & Media Center 164 Worldcup-ro Yeongtong-gu Suwon 16499 Korea / TEL : 031-219-5312 / FAX : 031-219-5314 Copyright (c) Ajou University Medical Information & Media Center All Rights Reserved. AJOU Open Repository는 국립중앙도서관 OAK 보급사업으로 구축되었습니다.