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Posterior circulation embolism as a potential mechanism for migraine with aura

Authors
Shin, DH; Lim, TS; Yong, SW; Lee, JS; Choi, JY; Hong, JM
Citation
Cephalalgia : an international journal of headache, 32(6):497-499, 2012
Journal Title
Cephalalgia : an international journal of headache
ISSN
0333-10241468-2982
Abstract
BACKGROUND: Although the mechanism of migraine is regarded as a functional disorder of the brain, numerous studies have reported that migraine is closely associated with vascular system abnormalities.



CASE REPORTS: We describe a 19-year-old female with recurrent migraine attacks and typical aura for 7 years. MRI showed multiple stroke lesions in the posterior circulation. Moreover, a pseudoaneurysm (1.9 × 1.4 cm) originating from the left vertebral artery was observed on four-vessel angiography. Multiple microembolic signals (MES) were repeatedly observed in the basilar artery using 30-minute transcranial Doppler monitoring. Interestingly, MES and her typical migrainous symptoms disappeared simultaneously with removal of the pseudoaneurysm.



DISCUSSION: This case supports the fact that microemboli play a pivotal role in the development of migraine attacks.
MeSH terms
Aneurysm, False/*complications/diagnosis/therapyCerebral AngiographyEmbolization, TherapeuticFemaleHumansIntracranial Embolism/*complications/pathology/surgeryMigraine with Aura/*etiologyStroke/*complications/diagnosis/therapyVertebral Artery/*pathology/surgeryYoung Adult
DOI
10.1177/0333102412441722
PMID
22523188
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Neurology
AJOU Authors
임, 태성용, 석우이, 진수최, 준영홍, 지만
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