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Clinical significance of right hepatectomy along the main portal fissure on donors in living donor liver transplantation

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dc.contributor.authorKim, BW-
dc.contributor.authorPark, YK-
dc.contributor.authorXu, W-
dc.contributor.authorWang, HJ-
dc.contributor.authorLee, JM-
dc.contributor.authorLee, K-
dc.date.accessioned2013-05-02T02:26:38Z-
dc.date.available2013-05-02T02:26:38Z-
dc.date.issued2012-
dc.identifier.issn0934-0874-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/8153-
dc.description.abstractThere might be discordance between inter-lobar borders of the main portal fissure (MPF) using the middle hepatic vein (MHV) and of the portal segmentation. Forty-five living donors who underwent right hepatectomy for the adult recipients from 2007 to 2011 in a tertiary hospital were retrospectively analyzed. The donors were classified into conventional right hepatectomy along the MPF (cRL group, n = 26) and modified right hepatectomy along right-side shifted transection plane from the MPF (mRL group, n = 19). The cRL donors had higher postoperative peak level of INR (1.84 vs. 1.62; P = 0.022), and bilirubin (3.37 mg/dl vs. 2.74 mg/dl; P = 0.065) than the mRL donors. cRL donors experienced greater depression of platelet count (144 per nL vs. 168 per nL; P = 0.042) and enlargement of splenic volume (52% vs. 37%; P = 0.025) than mRL donors for 7 days after hepatectomy. The regeneration of the left lateral sector was more accelerated in the cRL donors than the mRL donors for postoperative 3 months (148% vs. 84%; P = 0.015). There were no differences in the post-transplant graft function, incidence of complications, and graft survival rates between the two groups of recipients (P > 0.05). This study suggests that the conventional right hepatectomy along the MHV might increase donor risk by reducing parenchymal liver volume of the segment IV.-
dc.language.isoen-
dc.subject.MESHAdolescent-
dc.subject.MESHAdult-
dc.subject.MESHBiopsy-
dc.subject.MESHFemale-
dc.subject.MESHGraft Survival-
dc.subject.MESHHepatectomy-
dc.subject.MESHHepatic Veins-
dc.subject.MESHHumans-
dc.subject.MESHLiver-
dc.subject.MESHLiver Failure-
dc.subject.MESHLiver Transplantation-
dc.subject.MESHLiving Donors-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHRetrospective Studies-
dc.titleClinical significance of right hepatectomy along the main portal fissure on donors in living donor liver transplantation-
dc.typeArticle-
dc.identifier.pmid22805515-
dc.identifier.urlhttp://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0934-0874&date=2012&volume=25&issue=10&spage=1072-
dc.contributor.affiliatedAuthor김, 봉완-
dc.contributor.affiliatedAuthor박, 용근-
dc.contributor.affiliatedAuthor왕, 희정-
dc.contributor.affiliatedAuthor이, 재명-
dc.type.localJournal Papers-
dc.identifier.doi10.1111/j.1432-2277.2012.01538.x-
dc.citation.titleTransplant international-
dc.citation.volume25-
dc.citation.number10-
dc.citation.date2012-
dc.citation.startPage1072-
dc.citation.endPage1083-
dc.identifier.bibliographicCitationTransplant international, 25(10). : 1072-1083, 2012-
dc.identifier.eissn1432-2277-
dc.relation.journalidJ009340874-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Surgery
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