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Efficacy of veno-arterial extracorporeal membrane oxygenation in acute myocardial infarction with cardiogenic shock

DC Field Value Language
dc.contributor.authorKim, H-
dc.contributor.authorLim, SH-
dc.contributor.authorHong, J-
dc.contributor.authorHong, YS-
dc.contributor.authorLee, CJ-
dc.contributor.authorJung, JH-
dc.contributor.authorYu, S-
dc.date.accessioned2013-05-02T04:49:05Z-
dc.date.available2013-05-02T04:49:05Z-
dc.date.issued2012-
dc.identifier.issn0300-9572-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/8160-
dc.description.abstractAIM: We analyzed the results of acute myocardial infarction (AMI) complicated by cardiogenic shock (CS) necessitating extracorporeal membrane oxygenation (ECMO), and investigated for the associated risk factors for poor clinical outcomes.



METHODS: We retrospectively reviewed the medical records of 27 patients who required ECMO for AMI associated with CS between April 2006 and July 2010. Mean age was 63.7 ± 11.0 (range: 45-81) years, and there were 16 males (59.3%).



RESULTS: The mean duration of ECMO support was 30.2 ± 30.1 (range: 1-141)h. Cardiopulmonary resuscitations (CPR) were performed in 21 patients (77.8%) before ECMO initiation. Twenty-two patients (81.5%) were successfully weaned off ECMO, and 16 patients (59.3%) survived to discharge. The 30-day mortality was 37.0% (10/27 patients). Complications developed in 17 patients (63.0%: pneumonia in 10 patients, acute renal failure in 10 patients, massive bleeding in 4 patients, and thromboembolic event in 1 patient). The period between CPR initiation and ECMO commencement was a significant risk factor for ECMO weaning failure. High pre-ECMO serum lactate level was identified as a significant risk factor for poor survival on univariated and multivariated analysis.



CONCLUSION: ECMO support could improve survival in patients who suffer AMI associated with CS, and early ECMO initiation yields better outcomes (successful ECMO weaning).
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dc.language.isoen-
dc.titleEfficacy of veno-arterial extracorporeal membrane oxygenation in acute myocardial infarction with cardiogenic shock-
dc.typeArticle-
dc.identifier.pmid22322287-
dc.identifier.urlhttp://linkinghub.elsevier.com/retrieve/pii/S0300-9572(12)00056-1-
dc.contributor.affiliatedAuthor임, 상현-
dc.contributor.affiliatedAuthor홍, 유선-
dc.contributor.affiliatedAuthor이, 철주-
dc.type.localJournal Papers-
dc.identifier.doi10.1016/j.resuscitation.2012.01.037-
dc.citation.titleResuscitation-
dc.citation.volume83-
dc.citation.number8-
dc.citation.date2012-
dc.citation.startPage971-
dc.citation.endPage975-
dc.identifier.bibliographicCitationResuscitation, 83(8):971-975, 2012-
dc.identifier.eissn1873-1570-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Thoracic & Cardiovascular Surgery
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