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Effect of a distal protection device on epicardial blood flow and myocardial perfusion in primary percutaneous coronary intervention.

Authors
Zhou, BQ; Tahk, SJ
Citation
Journal of Zhejiang University. Science. B, 8(8):575-579, 2007
Journal Title
Journal of Zhejiang University. Science. B
ISSN
1673-15811862-1783
Abstract
OBJECTIVE: The beneficial effect of percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) has been well established, but there is the problem of no-reflow phenomenon which is an adverse prognostic factor in primary PCI. In the present study the effect of a distal protection device (PercuSurge GuardWire; GW) on epicardial blood flow and myocardial perfusion was evaluated.



METHODS AND RESULTS: Patients with AMI were randomly divided into 2 groups, the GW and the control groups. The GW group included 52 patients with AMI who underwent primary PCI with GW protection and the control group included 60 patients who underwent primary PCI without GW protection. Epicardial blood flow in the infarct-related artery (IRA) and myocardial perfusion were evaluated according to the thrombolysis in myocardial infarction (TIMI) flow grade and the myocardial blush grade (MBG). We found TIMI score of 3 was obtained significantly more frequently in the GW group (96%) than in the control group (80%). The MBG score of 3 was obtained also significantly greater in the GW group (65%) than in the control group (33%).



CONCLUSION: Primary PCI with GW protection can significantly improve epicardial blood flow and myocardial perfusion.
MeSH terms
AngiographyAngioplasty, Balloon, Coronary/*instrumentation/*methods*Coronary CirculationFemaleHumansMaleMiddle AgedMyocardial Infarction/surgeryMyocardial Reperfusion/*instrumentation/*methodsPerfusion
DOI
10.1631/jzus.2007.B0575
PMID
17657860
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
AJOU Authors
탁, 승제
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