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The Relationship of epicardial adipose tissue to metabolic syndrome and cardiovascular risk factors.

Other Title
심장외막지방과 대사 증후군 및 심혈관 질환 위험인자와의 연관성
Authors
백, 승희; 안, 성균; 최, 정현; 고, 보람; 유, 준환; 강, 수진; 최, 병주; 최, 소연; 윤, 명호; 탁, 승제; 신, 준한
Citation
The Korean journal of medicine, 72(3):290-297, 2007
Journal Title
The Korean journal of medicine; 대한내과학회지
ISSN
1738-93642289-0769
Abstract
Background: Increased adiposity is widely accepted as the main expression of obesity and an important risk factor for the development of cardiovascular and metabolic syndrome. The significance of epicardial adipose tissue (EAT), frequently observed during a transthoracic echocardiographic examination, is not well recognized. The purpose of this study was to investigate the relationship of EAT to metabolic syndrome and cardiovascular risk factors.



Methods: We collected clinical, biochemical, and anthropometric information from 289 consecutive and prospective patients (147 men; 59+/-11 years) who visited our hospital for a complaint of chest pain. EAT thickness was measured by transthoracic echocardiography on the free wall of the right ventricle in the parasternal long axis and short axis views at the base level during end-diastole.



Results: EAT thickness was significantly increased in 185 (64%) patients with metabolic syndrome as compared with patients without metabolic syndrome (4.3+/-2.5 mm vs. 3.6+/-2.8 mm, p=0.005). By a simple linear regression analysis, EAT was correlated to age (r=0.484, p<0.001), waist circumference (r=0.177, p=0.01), the level of HDL cholesterol (r=-0.182, p=0.001) and log CRP (r=0.268, p=0.012). Multivariate analysis showed that age and log CRP were the independent variables that correlated to EAT thickness.



Conclusion: These results suggest that echocardiographic EAT should be considered as a new useful imaging indicator of visceral adipose tissue related to metabolic syndrome and cardiovascular disease.
Keywords
심장외막지방경흉부 심초음파대사 증후군심혈관 질환위험인자Epicardial adipose tissueEchocardiographyMetabolic syndrome XCardiobascular diseaseRisk factors
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Pulmonary & Critical Care Medicine
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
AJOU Authors
백, 승희강, 수진최, 병주최, 소연윤, 명호탁, 승제신, 준한
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