Cited 0 times in Scipus Cited Count

The Effect of Nitrous Oxide on Cerebral Entropy during Isoflurane Inhalational Anesthesia

Other Title
Isoflurane 흡입마취 동안 아산화질소가 뇌 엔트로피에 미치는 영향
Authors
박, 관식  | 박, 정국 | 문, 봉기  | 이, 숙영  | 김, 진수  | 노, 현주
Citation
The Journal of the Korean Society of Anesthesiologists, 52(5). : 543-549, 2007
Journal Title
The Journal of the Korean Society of Anesthesiologists
ISSN
0302-5780
Abstract
Background: The bispectral index has limitations in describing the exact depth of anesthesia during nitrous oxide inhalation. This study examined the effect of nitrous oxide on the cerebral entropy measured using an entropy module (M-ENTROPY Module S/5?, Datex-Ohmeda division, Instrumentarium Corporation, Helsinki, Finland) during the stable anesthetic period with isoflurane inhalation.



Methods: Sixty ASA 1 or 2 adult patients were randomly allocated to three groups. During the stable maintenance period after the skin incision, the baseline entropy values (response entropy, RE; state entropy, SE) were recorded at 2.5 minutes intervals over a 20 minute period on a single frontal channel at 0.9% end-tidal isoflurane. After this, medical air was used continuously (group C) or replaced with nitrous oxide at 40% (group L) or 60% (group H) with continuous hemodynamic and entropy values monitoring. Each of the variables was recorded and analyzed at 2.5 minutes intervals over a 20 minute period.



Results: Average values (mean ± SD) of the RE and SE during experimental period were lower in group H (29.2 ± 12.3 and 28.5 ± 11.7, respectively) than group L (33.9 ± 7.3 and 33.0 ± 7.3, respectively) and the averaged values were lower in group L than in group C (46.6 ± 14.8 and 45.5 ± 14.2, respectively). The percent reduction was larger in group H (42.1 ± 14.2 and 38.7 ± 16.5, respectively) than in group L (25.3 ± 15.1 and 24.4 ± 14.9, respectively) and the percent reduction was larger in group L than in group C (P < 0.01).



Conclusions: Added nitrous oxide during the anesthetic maintenance period with isoflurane decreases the level of cerebral entropy.
Keywords

Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Anesthesiology & Pain Medicine
Ajou Authors
김, 진수  |  문, 봉기  |  박, 관식  |  이, 숙영
Full Text Link
Files in This Item:
The Journal of the Korean Society of Anesthesiologists_52(5)_543-549.pdfDownload
Export

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse