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Assessment of the Image Quality and Diagnostic Accuracy of Coronary CT Angiography: Effect of Sublingual Administration of Nitroglycerin

Other Title
관상동맥 CT조영술의 화질과 진단 정확도: 설하 니트로글리세린의 효과
Authors
강, 두경; 노, 현우; 박, 경주; 최, 소연
Citation
Taehan Yŏngsang Ŭihakhoe chi, 56(2):127-135, 2007
Journal Title
Taehan Yŏngsang Ŭihakhoe chi; Journal of the Korean Radiological Society; Journal of the Korean Society of Radiology; 대한영상의학회지
ISSN
1738-26372288-2928
Abstract
Purpose: We wanted to investigate the effect of sublingual nitroglycerin (NTG) on improving the image quality and diagnostic accuracy of coronary computed tomographic angiography (CTA) for detecting atherosclerosis and significant stenosis.



Materials and Methods: We retrospectively assessed the data of 81 patients who underwent coronary CTA. Forty three patients underwent coronary CTA without medication (the non-administrated group), while 38 patients were given 0.6 mg NTG sublingually before coronary CTA (the administrated group). Image quality was assessed using a five-point grading scale. We evaluated the diagnostic performance of coronary CTA for assessing atherosclerosis and significant stenosis (?50%) in the 42 patients who underwent invasive coronary angiography.



Results: The mean image-quality grades were 4.09+/-0.72 and 4.50+/-0.60 in the non-administrated and administrated groups, respectively (p=0.008). On the per-artery analysis, the accuracy percentages for detecting coronary CTA were 65 and 88% for atherosclerosis and 82 and 80% for significant stenosis in the non-administrated and administrated groups, respectively. On the per-patient analysis, the positive predictive values for coronary CTA were 80% and 100% for atherosclerosis and 77% and 88% for significant stenosis in the non-administrated and administrated groups, respectively.



Conclusion: Coronary CTA with NTG administration improved the image quality. The accuracy of coronary CTA for detecting atherosclerosis was higher in the administrated group than in the non-administrated group.
Keywords
Computed tomography(CT) angiographyCoronary angiographyDrugsHeart effects of drugs on
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
Journal Papers > School of Medicine / Graduate School of Medicine > Radiology
AJOU Authors
강, 두경박, 경주최, 소연
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