Cited 0 times in Scipus Cited Count

Clinical Behaviors and Treatment Outcome of Papillary Thyroid Microcarcinomas:Tumor Size-Based Therapeutic Concept

DC Field Value Language
dc.contributor.author이, 잔디-
dc.contributor.author오, 동규-
dc.contributor.author임, 승수-
dc.contributor.author남, 기현-
dc.contributor.author정, 웅윤-
dc.contributor.author소, 의영-
dc.contributor.author박, 정수-
dc.date.accessioned2014-01-08-
dc.date.available2014-01-08-
dc.date.issued2008-
dc.identifier.issn1229-5183-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/8814-
dc.description.abstractPurpose: The incidence of papillary thyroid microcarcinoma(PTMC) has increased due to the widespread use of high resolution ultrasonography and fine-needle aspiration biopsy. However, the clinical and biologic behaviors of PTMC is debatable. The aim of this study was to describe clinicopathologic features of PTMC and to suggest whether tumor size(5mm) might prove the useful parameter for determining the surgical strategy in PTMC.



Materials and Methods: From Jan. 2000 to Dec. 2005, 1355 of 2678 patients with papillary thyroid carcinoma were identified as having PTMC, based on tumor size10mm(50.6%). Among patients with PTMC, we further separated tumors<5mm(minute group:group M) from those 5 to 10mm(tiny group:group T). We compared the clinicopathological characteristics and the TNM stagings between two groups.



Results: There were 114(8.4%) men and 1241(91.6%) women with a median age of 47 years(range;13-79). During a mean follow-up of 47.3(range;22-93), 13 patients(1.0%) developed locoregional recurrences and 3 patients(0.2%) showed distant metastases at initial presentation. Statistical analysis revealed that the presence of extracapsular invasion(p<0.0001), invasion to adjacent structure(p<0.0001), multifocality(p<0.0001), central lymph node metastasis(p<0.0001), and lateral lymph node metastasis(p<0.0001) were all significantly higher in tiny group(tumor5mm). Furthermore, minute group demonstrated a significantly lower tumor stage(AJCC TNM classification) compared with tiny group(p<0.0001).



Conclusion: Patients with PTMC have a favorable treatment outcomes, although the distinction needs to be made with reference to the clinicopathologic behaviors. It would be reasonable to consider that tumor size(5mm) would be useful parameter for the treatment strategy of PTMC.
-
dc.language.isoko-
dc.titleClinical Behaviors and Treatment Outcome of Papillary Thyroid Microcarcinomas:Tumor Size-Based Therapeutic Concept-
dc.title.alternative미세 유두 갑상선암의 크기에 따른 임상상 및 단기간 치료 결과-
dc.typeArticle-
dc.subject.keyword유두 미세 갑상선암-
dc.subject.keyword임상상-
dc.subject.keyword극미소암-
dc.subject.keyword미소암-
dc.subject.keyword치료결과-
dc.subject.keywordPapillary thyroid microcarcinoma-
dc.subject.keywordClinical behaviors-
dc.subject.keywordMinute carcinoma-
dc.subject.keywordTiny carcinoma-
dc.subject.keywordTreatment outcome-
dc.contributor.affiliatedAuthor이, 잔디-
dc.contributor.affiliatedAuthor소, 의영-
dc.type.localJournal Papers-
dc.citation.titleKorean journal of head & neck oncology-
dc.citation.volume24-
dc.citation.number1-
dc.citation.date2008-
dc.citation.startPage47-
dc.citation.endPage52-
dc.identifier.bibliographicCitationKorean journal of head & neck oncology, 24(1). : 47-52, 2008-
dc.identifier.eissn2586-2553-
dc.relation.journalidJ012295183-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Surgery
Files in This Item:
There are no files associated with this item.

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse