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신장이식후 발생한 유두상 갑상선암

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dc.contributor.author이, 잔디-
dc.contributor.author홍, 협-
dc.contributor.author정, 종주-
dc.contributor.author남, 기현-
dc.contributor.author정, 웅윤-
dc.contributor.author소, 의영-
dc.contributor.author박, 정수-
dc.description.abstractPurpose: The chronic use of immunosuppressive therapy in transplant recipients can increase the long-term risk of carcinoma. The aim of this study was to determine the incidence, biological behaviors, and treatment outcomes in PTC(papillary thyroid carcinoma) in renal allograft recipients.

Materials and Methods: The present study examined the incidence and biological behavior of PTCs in RA recipients. A total of 1,739 RA patients treated between January 1986 and December 1999 were followed-up for a median 137(84-238) months. During the follow-up period, 129(7.4%) recipients were identified as having posttransplant malignancies. Of those, 12(0.7%) had PTCs, and these comprised six male and six female patients with a median age of 41(23-57) years.

Results: Nine cases(incidentalomas) were diagnosed based on ultrasonography(US) screening. Eight of those nine were TNM stage I, and two of the three clinical carcinomas were TNM stage IVa. During a median follow-up of 94(18-159) months, two(16.7%) PTC patients developed loco-regional recurrence, but no patients showed distant metastasis. Posttransplant PTC showed no gender bias, and was often associated with aggressive lymphatic metastasis. However, most incidentalomas showed a favorable treatment outcome.

Conclusion: In conclusion, routine surveillance of the thyroid gland using US screening is recommended to ensure early detection, treatment and favorable prognosis in RA patients with PTC.
dc.title신장이식후 발생한 유두상 갑상선암-
dc.subject.keyword이식후 발생한 악성종양-
dc.subject.keyword유두상 갑상선암-
dc.subject.keywordPosttransplant malignancy-
dc.subject.keywordPTC(papillary thyroid carcinoma)-
dc.subject.keywordRenal allograft-
dc.contributor.affiliatedAuthor이, 잔디-
dc.contributor.affiliatedAuthor소, 의영-
dc.type.localJournal Papers-
dc.citation.titleKorean journal of head & neck oncology-
dc.identifier.bibliographicCitationKorean journal of head & neck oncology, 24(1):64-68, 2008-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Surgery
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