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A Congenital Giant hepatic hemangioendothelioma Treated with Interferon-a and Complete Tumor Resection

Other Title
인터페론 투여 후 완전 절제를 시행한 거대 선천성 간내 혈관내피종
Authors
조, 민아; 유, 재은; 박, 문성; 박, 준은; 홍, 정; 김, 영배
Citation
Neonatal medicine, 15(2):183-189, 2008
Journal Title
Neonatal medicine; 대한신생아학회지
ISSN
2287-94122287-9803
Abstract
Infantile hepatic hemangioendotheliomas (IHHEs) are benign vascular tumors, but can be associated with the life-threatening complications, such as congestive heart failure, disseminated intravascular coagulation, and massive bleeding. Various therapeutic options have been developed and the treatment response depends on the patient's clinical status and the nature of the lesion. In the case of a symptomatic IHHE, a non-invasive and precise diagnosis should be performed promptly before the therapeutic method is chosen. Additionally, it should be kept in mind that the residual lesions have malignant potential. We report a case of a congenital giant IHHE that was successfully reduced in size by interferon-α and completely removed by surgical tumor resection with a hepatic lobectomy.

신생아의 선천성 거대 간내 혈관내피종을 복부 단층촬영과 99mTc-RBC 간스캔을 통해 진단하고, 대증요법과 함께 IFNα를 11개월간 단독으로 피하 투여하여 크기 감소를 유도한 후 남은 병변의 완전한 수술적 제거와 조직학적 확진을 시행하였음을 보고하는 바이다.
Keywords
Infantile hepatic hemangioendotheliomaInterferon-α
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Surgery
Journal Papers > School of Medicine / Graduate School of Medicine > Pathology
Journal Papers > School of Medicine / Graduate School of Medicine > Pediatrics & Adolescent Medicine
AJOU Authors
유, 재은박, 문성박, 준은홍, 정김, 영배
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