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A Case of Primary Hyperparathyroidism with Pathologic Fracture, Osteitis Fibrosa Cystica and Hungry Bone Syndrome, Recovered after Parathyroidectomy

Other Title
부갑상선 수술 후 회복된 병적 골절, 낭성섬유골염, Hungry Bone Syndrome을 동반한 원발성 부갑상선 기능항진증 1예
Authors
김, 순선; 정, 윤석; 이, 두형; 김, 태호; 이, 기범; 이, 진우; 황, 의경; 곽, 규성
Citation
Journal of bone metabolism, 16(1):59-64, 2009
Journal Title
Journal of bone metabolism
ISSN
2287-63752287-7029
Abstract
Severe parathyroid bone disease is a rare clinical presentation of primary hyperparathyroidism. Nowadays primary hyperparathyroidism is diagnosed in an early phase mainly due to the routine use of multi-channel chemical blood screening. We experienced a case of 34 year-old male with primary hyperparathyroidism presenting with pathological femur neck fracture. The patient was presented with fracture of the right femur neck after slip down, and was diagnosed as having primary hyperparathyroidism. Ultrasonography and Tc-99m sestamibi scan revealed an enlarged left inferior parathyroid gland. Tumor was operated and pathologically confirmed to be a parathyroid adenoma. A few days after operation, he developed tingling sensation of perioral area and both hands, which was found to be due to hungry bone syndrome. Calcium, vitamin D, and magnesium supplements were administered. Long term follow-up of blood chemistry revealed recovery of biochemical markers including alkaline phosphatase, calcium, phosphorous, and magnesium. After 9 months, CT (computed tomography) of the pelvis showed decreased porosity and cystic lesions around the femur, and DXA (dual-energy X-ray absorptiometry) revealed markedly increased bone mineral densities in the spine and femur compared with preoperative data.
Keywords
Osteitis fibrosa cysticaPrimary hyperparathyroidismRecovery with follow-up
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Gastroenterology
Journal Papers > School of Medicine / Graduate School of Medicine > Orthopedic Surgery
Journal Papers > School of Medicine / Graduate School of Medicine > Pathology
Journal Papers > School of Medicine / Graduate School of Medicine > Radiology
Journal Papers > School of Medicine / Graduate School of Medicine > Endocrinology & Metabolism
AJOU Authors
김, 순선정, 윤석이, 두형김, 태호이, 기범곽, 규성
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