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A Comparison Study of Two Different Methods of Administration: Intranasal versus Intramuscular for Pediatric Procedural Sedation and Analgesia

Other Title
소아의 통증성 술기에 있어 Ketamine 비강내 투여와 근육 주사의 진정 정도 비교 연구
안, 경찬; 안, 정환; 이, 국종; 정, 윤석; 최, 상천; 조, 영신; 이, 지숙; 이, 정아; 김, 기운
Taehan Ŭnggup Ŭihakhoe chi, 20(4):422-427, 2009
Journal Title
Taehan Ŭnggup Ŭihakhoe chi; Journal of the Korean Society of Emergency Medicine; 대한응급의학회지
Purpose: To compare the efficacy of ketamine between intranasal (IN) administration and intramuscular (IM) injection for pediatric procedural sedation and analgesia (PPSA).

Methods: A prospective study was conducted during 3 months. Ketamine was given by IN or IM route before primary repair of facial laceration for procedural sedation. The administration dose was 8 mg/kg for IN and 4 mg/kg for IM. We evaluated resistance scale on administration, sedation scale, satisfaction of physician and parents.

Results: One hundred children were enrolled into this study. IN administration was given to 50 children, and IM injection to 50 children each. In the IN group, 75%(36 of 50) showed severe resistance, whereas only 34%(17 of 50) showed severe resistance and 50%(25 of 50) showed mild resistance in IM group. Successful rate of sedation after initial administration was 82%(41 of 50) in IM group and 34% in IN group. Satisfaction of physicians and parents was high in IM injection group.

Conclusion: Intranasal administration of Ketamine is less effective and provides lower satisfaction than intramuscular injection for procedural sedation of pediatric patients in the emergency department.
Intranasal AdministrationIntramuscular InjectionKetamineConscious Sedation
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Surgery
Journal Papers > School of Medicine / Graduate School of Medicine > Emergency Medicine
AJOU Authors
안, 정환이, 국종정, 윤석최, 상천이, 지숙이, 정아김, 기운
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