Three cases of acute peritoneal dialysis in acute pancreatitis patients complicated by acute renal failure

Abstract

저자들은 급성 췌장염 환자에서 급성 신부전이 동반된 경우 복막투석으로 복강 세척 및 배액을 통해 급성 췌장염의 임상적 증상 호전 및 전신적 합병증을 감소시키고, 급성신부전의 호전으로 소변량 증가와 함께 신기능이 회복된 3예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Severe acute pancreatitis occurs in about 20% of patients with acute pancreatitis and can be associated with multiorgan failure. Acute renal failure caused by severe acute pancreatitis not only aggravates pancreatitis but also increases patient mortality. Peritoneal exudate contains many toxic substances such as amylase, lipase, phospholipase-A, trypsinogen, prostaglandins, kinin forming enzymes, and histamine releasing factor. Upon entering the circulation, these substances can cause complications, which are responsible for the majority of early deaths. This said, peritoneal dialysis is indicated to remove toxic materials from the peritoneal cavity and to manage acute renal failure. We report three acute peritoneal dialysis cases in acute renal failure associated with severe acute pancreatitis.