Posterior Reversible Encephalopathy Syndrome in a Patient with Lupus Nephritis
루푸스신염에 동반된 가역적 후두부 뇌병증 증후군
김, 현경; 김, 현아; 장, 은정; 서, 창희
The Journal of the Korean Rheumatism Association, 17(2):177-182, 2010
The Journal of the Korean Rheumatism Association; 대한류마티스학회지
Posterior reversible encephalopathy syndrome (PRES) has been described in various clinical settings, including severe hypertension, eclampsia, lupus and immunosuppressive therapy. We report a 27 year-old female systemic lupus erythematosus patient who developed severe headache, seizure and hemiparesis during her lupus nephritis flare. Magnetic resonance image (MRI) showed multi-focal high signal intensity lesions in the parieto-occipital cortex bilaterally and in the subcortical white matter. Her condition improved with immunosuppressive treatments, antihypertensives and hemodialysis. The extent of her lesions decreased on follow-up MRI 2 months later. This case suggests that PRES can be treated with immunosuppressive drugs that do not increase blood pressure.
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