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A Case of High Dose Oseltamivir Treatment in an Influenza A (H1N1) Infected Patient with Severe Graft Versus Host Disease

Other Title
Influenza A (H1N1) 감염된 중증 이식편대 숙주병을 가진 환아에서 고용량 Oseltamivir 치료경험 1예
Authors
김, 아름; 김, 은심; 배, 기수; 박, 준은
Citation
Clinical pediatric hematology-oncology, 18(1):58-61, 2011
Journal Title
Clinical pediatric hematology-oncology
ISSN
2233-52502233-4580
Abstract
Influenza A (H1N1) infection has been noted to be common in the young and high-risk groups for influenza infection, including transplant candidates and recipients. However, the optimal dosage and duration of oseltamivir for severely immunocompromised patients have not been defined. We report the case of a patient with relapsed neuroblastoma who was infected with influenza A (H1N1) and suffered from skin and lung graft versus host disease after he had received allogeneic hematopoietic stem cell transplantation from a matched sibling donor. During the immunosuppressant therapy, he was diagnosed with influenza A (H1N1) infection by real time polymerase chain reaction (RT-PCR). He recovered after oseltamivir treatment with a dosage of 90 mg twice a day for two weeks, which was two times of the standard dose until influenza A (H1N1) RT-PCR was proven to be negative.
Keywords
H1N1 virusGraft vs host diseaseTransplantationHomologous
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Pediatrics & Adolescent Medicine
AJOU Authors
배, 기수박, 준은
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