Clinical Efficacy of Korean FRAXⓡ Model in Patients with Hip Fracture
고관절 골절환자에서 한국인 FRAX® 모델의 효용성
지, 형민; 원, 예연; 박, 민정
Osteoporosis, 9(2):170-174, 2011
Objectives:We aimed to examine clinical efficacy of Korean FRAX model with respect to prediction of osteoporotic fracture risk and eligibility of osteoporosis treatment in Korean patients with hip fractures.
Materials and Methods: In 41 elderly patients with a proximal femoral fracture (mean age=78.7 years, range: 63～99 years), fracture probabilities were calculated using FRAX models from Korea and Japan. We then performed comparative analyses between ten-year probabilities of major / hip osteoporotic fractures and the osteoporosis treatment eligibilities based on the FRAX model from Korea and Japan.
Results:The mean ten-year probabilities of major osteoporotic fractures and hip fractures using the Korean FRAX model (11.5% and 5.9%, respectively) were significantly lower than those using the Japanese FRAX model (21.5% and 9.2%, respectively, P<0.001). In addition, based on the National Osteoporosis Foundation guideline, pharmacological treatment of osteoporosis would be recommended in 38 patients (92.7%) by the Japanese FRAX model, while only in 30 patients (73.2%) by the Korean FRAX model (P= 0.037).
Conclusions:Our results suggest that the Korean FRAX model might underestimate osteoporotic fracture probabilities and eligibility of osteoporosis treatment in Korean patients with hip fracture.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
Total Visit :3,861,155
Total Download :1,622,181
Today View :596
Ajou University Medical Information & Media Center 164 Worldcup-ro Yeongtong-gu Suwon 16499 Korea / TEL : 031-219-5312 / FAX : 031-219-5314 Copyright (c) Ajou University Medical Information & Media Center All Rights Reserved. AJOU Open Repository는 국립중앙도서관 OAK 보급사업으로 구축되었습니다.