207 315

Cited 0 times in

Reduction of the Nailfold Capillary Blood Velocity in Cigarette Smokers

Authors
Kim, KM; Lee, DJ; Joo, NS
Citation
Korean Journal of Family Medicine, 33(6):398-405, 2012
Journal Title
Korean Journal of Family Medicine; 가정의학회지
ISSN
2005-64432092-6715
Abstract
Background: Cigarette smoking causes cardiovascular disease and activates markers of endothelial dysfunction or injury. We investigated the nailfold capillary blood velocity (NCV) in cigarette smokers compared to non-smokers.



Methods: Forty-eight men (eighteen non-smokers and thirty smokers) were recruited. We measured NCV using nailfold capillary microscopy and exhaled carbon monoxide (ECO) concentration three times (before smoking; NCV0min and ECO0min, and after smoking; NCV5min, ECO5min, NCV30min, and ECO30min), in a condition of fasting in the case of smokers. In non-smokers, the same measurements were taken without smoking. Additionally, personal cigarette smoking and alcohol drinking history were acquired by a self-administrated questionnaire.



Results: Mean age, waist circumference, ECO0min, ECO5min, and ECO30min was higher and NCV5min and NCV30min were significantly lower in smokers compared to non-smokers. Total smoking years were negatively correlated with NCV5min. Average pack of the daily smoking, total pack-years, as well as total smoking years were also negatively correlated with NCV30min by regression analysis. After adjustment of significantly different variables, NCV30min was significantly lower in smokers. In the subgroup analysis, the interleukin-6 level was significantly increased in subjects with a long period of cigarette smoking compared with non-smokers.



Conclusion: Reduction of NCV in smokers is associated with personal smoking history, not with body composition or certain oxidative stress markers.
Keywords
Nailfold Capillary Blood VelocitySmokingQxidative Stress
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Family Practice & Community Health
AJOU Authors
김, 광민이, 득주주, 남석
Files in This Item:
Korean Journal of Family Medicine_33(6)_398-405.pdfDownload
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse