Cited 0 times in Scipus Cited Count

The effect of acute auditory stress on gastric motor responses to a meal in healthy volunteers.

DC Field Value Language
dc.contributor.authorLee, HS-
dc.contributor.authorAn, YS-
dc.contributor.authorKang, J-
dc.contributor.authorYoo, JH-
dc.contributor.authorLee, KJ-
dc.date.accessioned2014-05-15T01:42:40Z-
dc.date.available2014-05-15T01:42:40Z-
dc.date.issued2013-
dc.identifier.issn0815-9319-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/9966-
dc.description.abstractBACKGROUND AND AIM: Stress is believed to play a role in the pathogenesis of functional gastrointestinal disorders. The aim of the present study was to investigate the effect of acute auditory stress on gastric motor responses to a meal in healthy subjects.



METHODS: A total of eight healthy volunteers (seven men and one woman; median age, 33.4 years [30-35 years]) who had no recurrent gastrointestinal symptoms participated in the prospective, randomized, crossover study. Gastric half-emptying time and meal-induced proximal gastric accommodation were measured using gastric scintigraphy under the auditory stress and control conditions in a randomized crossover design.



RESULTS: The gastric half-emptying time under the stress condition was significantly longer than that under the control condition (130.8 ± 16.6 vs. 105.0 ± 13.1 min; P = 0.005 by paired t-test). Under the stress and control conditions, the proximal gastric volume significantly increased after a meal (P < 0.001 by repeated measures analysis of variance). The degree of the postprandial increase in proximal gastric volume did not significantly differ between both conditions (P = 0.598 by tests of between-subjects effects using repeated measures analysis of variance). The severity scores of postprandial epigastric discomfort and fullness were significantly higher under the stress condition than under the control condition (P = 0.001 and P = 0.039, respectively, by paired t-test).



CONCLUSIONS: Acute auditory stress delays gastric emptying and increases the severity of postprandial symptoms in the healthy subjects, suggesting the relevance of psychological stress to the pathophysiological mechanism of functional dyspepsia.
-
dc.language.isoen-
dc.subject.MESHAcoustic Stimulation-
dc.subject.MESHAdult-
dc.subject.MESHDyspepsia-
dc.subject.MESHFemale-
dc.subject.MESHGastric Emptying-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHPostprandial Period-
dc.subject.MESHStress, Psychological-
dc.titleThe effect of acute auditory stress on gastric motor responses to a meal in healthy volunteers.-
dc.typeArticle-
dc.identifier.pmid23800263-
dc.contributor.affiliatedAuthor안, 영실-
dc.contributor.affiliatedAuthor강, 준구-
dc.contributor.affiliatedAuthor유, 준환-
dc.contributor.affiliatedAuthor이, 광재-
dc.type.localJournal Papers-
dc.identifier.doi10.1111/jgh.12309-
dc.citation.titleJournal of gastroenterology and hepatology-
dc.citation.volume28-
dc.citation.number11-
dc.citation.date2013-
dc.citation.startPage1699-
dc.citation.endPage1704-
dc.identifier.bibliographicCitationJournal of gastroenterology and hepatology, 28(11). : 1699-1704, 2013-
dc.identifier.eissn1440-1746-
dc.relation.journalidJ008159319-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Nuclear Medicine & Molecular Imaging
Journal Papers > School of Medicine / Graduate School of Medicine > Gastroenterology
Files in This Item:
There are no files associated with this item.

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse