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Periprocedural myocardial infarction is not associated with an increased risk of long-term cardiac mortality after coronary bifurcation stenting.

DC Field Value Language
dc.contributor.authorSong, PS-
dc.contributor.authorSong, YB-
dc.contributor.authorYang, JH-
dc.contributor.authorKang, GH-
dc.contributor.authorHahn, JY-
dc.contributor.authorChoi, SH-
dc.contributor.authorChoi, JH-
dc.contributor.authorLee, SH-
dc.contributor.authorJang, Y-
dc.contributor.authorYoon, JH-
dc.contributor.authorTahk, SJ-
dc.contributor.authorSeung, KB-
dc.contributor.authorPark, SJ-
dc.contributor.authorGwon, HC-
dc.date.accessioned2014-05-19T05:08:50Z-
dc.date.available2014-05-19T05:08:50Z-
dc.date.issued2013-
dc.identifier.issn0167-5273-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/9999-
dc.description.abstractBACKGROUND: Debate continues over the importance of periprocedural myocardial infarction (PMI) after percutaneous coronary intervention (PCI). We evaluated the prognostic significance of PMI in patients undergoing PCI for bifurcation lesions.



METHODS: Between January 2004 and June 2006, patients from 16 centers who received non-left main bifurcation lesion PCIs were enrolled. PMI was defined as a peak creatine kinase-myocardial band (CK-MB) ≥ 3 times the upper limit of normal after PCI. We compared long-term cardiac mortality between patients with and without PMI.



RESULTS: Among the 1188 patients, PMI occurred in 119 (10.0%). Left ventricular ejection fraction<50% (adjusted hazard ratio [HR]: 2.08, 95% confidence interval [CI]: 1.13-3.82, p=0.018), multi-vessel coronary artery disease (adjusted HR: 2.28, 95% CI: 1.36-3.81, p=0.002), and PCI-related acute closure in a side branch (adjusted HR: 3.34, 95% CI: 1.23-9.02, p=0.018) were the significant risk factors for PMI. During the median follow-up of 22.7 months, the unadjusted rate of long-term cardiac mortality was significantly higher in patients with PMI than in those without PMI (2.5% vs. 0.7%, p=0.026). After multivariable adjustment, the relationship between PMI and short-term (≤ 30 day) cardiac mortality was significant (adjusted HR: 12.32, 95% CI: 1.07-141.37, p=0.044). However, PMI was not an independent prognostic factor of long-term cardiac mortality (adjusted HR: 2.59, 95% CI: 0.62-10.85, p=0.20).



CONCLUSIONS: PMI occurs in patients with a higher prevalence of adverse cardiac risks and predicts short-term but not long-term cardiac mortality in patients undergoing bifurcation lesion PCI.
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dc.language.isoen-
dc.subject.MESHAged-
dc.subject.MESHCoronary Artery Disease/*mortality/surgery-
dc.subject.MESH*Drug-Eluting Stents/adverse effects-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMyocardial Infarction/*diagnosis/*mortality/surgery-
dc.subject.MESH*Preoperative Period-
dc.subject.MESHRegistries-
dc.subject.MESHRisk Factors-
dc.subject.MESHTime Factors-
dc.subject.MESHTreatment Outcome-
dc.titlePeriprocedural myocardial infarction is not associated with an increased risk of long-term cardiac mortality after coronary bifurcation stenting.-
dc.typeArticle-
dc.identifier.pmid22494861-
dc.identifier.urlhttp://linkinghub.elsevier.com/retrieve/pii/S0167-5273(12)00353-1-
dc.contributor.affiliatedAuthor탁, 승제-
dc.type.localJournal Papers-
dc.identifier.doi10.1016/j.ijcard.2012.03.146-
dc.citation.titleInternational journal of cardiology-
dc.citation.volume167-
dc.citation.number4-
dc.citation.date2013-
dc.citation.startPage1251-
dc.citation.endPage1256-
dc.identifier.bibliographicCitationInternational journal of cardiology, 167(4):1251-1256, 2013-
dc.identifier.eissn1874-1754-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
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