2026-09-22T08:37:21Zhttps://repository.ajou.ac.kr/oai/request

oai:repository.ajou.ac.kr:201003/12672024-10-11T02:17:38Zcom_201003_14369com_201003_14368col_201003_14370

이, 관우 김, 은경 대학원 의학과 200724495 김, 은경 2011-01-26T01:03:36Z 2011-01-26T01:03:36Z 2010 2010 http://repository.ajou.ac.kr/handle/201003/1267 http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000010873 000000010873 Objective: Dietary fiber improves metabolic syndrome by improving obesity, hyperglycemia, hyperinsulinemia and hypercholesterolemia. There has been a growing need for a new source of dietary fiber. We evaluated the clinical effect of dietary fiber derived from lees of brown rice in type 2 diabetes and assessed the potential of lees of brown rice as a new source of dietary fiber. Methods: This study is a randomized, double-blinded, placebo-controlled study, scheduled for 12 weeks. Thirty subjects were randomly assigned to receive either a dietary fiber supplement from lees of brown rice (LB) or a mixed-grain based dietary product (MG). The body weight, waist circumference, body composition, lipid profiles and other laboratory parameters were measure at baseline and at the 12th week. Results: The LB group showed greater reduction in waist (-2.80 -cm vs -0.93 cm, p=0.032) and hip circumferences (-1.00 cm vs 0.92 cm, p=0.017) compared to the MG group. In addition, the consumption of LB resulted in significant lower levels of aspartate transaminase (-4.36 IU/ml vs -0.07 IU/ml, p=0.044) and alanine transaminase (-6.64 IU/ml vs 0.07 IU/ml, p=0.038) than diet with MG. The additive dietary fiber diet with LB had a tendency to increase interluekin 10 (0.63 pg/ml vs -0.91 pg/ml, p=0.518) and to decrease interluekin 6 (-1.00 pg/ml vs 0.24 pg/ml, p=0.277) compared to the diet with MG. Conclusions: In conclusion, this study revealed that the dietary fiber from lees of brown rice reduces waist and hip circumferences in type 2 diabetes. Approved for entry into archive by Hyun Chul Cho (hccho@ajou.ac.kr) on 2011-01-26T01:03:36Z (GMT) No. of bitstreams: 1 000000010873.pdf: 571464 bytes, checksum: bfe89ecd96fad1647af94a6295323ef7 (MD5) Made available in DSpace on 2011-01-26T01:03:36Z (GMT). No. of bitstreams: 1 000000010873.pdf: 571464 bytes, checksum: bfe89ecd96fad1647af94a6295323ef7 (MD5) Submitted by Hyun Chul Cho (hccho@ajou.ac.kr) on 2011-01-26T01:03:36Z No. of bitstreams: 1 000000010873.pdf: 571464 bytes, checksum: bfe89ecd96fad1647af94a6295323ef7 (MD5) ABSTRACT TABLE OF CONTENTS LIST OF TABLES Ⅰ. INTRODUCTION Ⅱ. MATERIALS AND METHODS A. SUBJECTS B. EXPERIMENTAL DESIGN C. LEES EXTRACTS CPMPONETN ANALYSIS D. MEASUREMENT 1. BMI 2. Body composition 3. Blood pressure and heart rate 4. Laboratory analysis 5. Oral glucose tolerance test 6. Statistical analysis Ⅲ. RESULTS Ⅳ. DISCUSSION REFERENCES 국문요약 Master en Effects of Lees from Brown Rice on Waist Circumference and Metabolic Parameters in Type 2 Diabetes: A Randomized, Double-blinded, Placebo-controlled Trial 제 2형 당뇨병 환자에서의 발효곡류 섬유소의 임상적 효과: 무작위 이중 맹검 위약-대조군 연구 Thesis Theses dietary fiber type 2 diabetes 2010 9999-12-31 9999-12-31