97 282

Cited 32 times in

Genetics of hypersensitivity to aspirin and nonsteroidal anti-inflammatory drugs.

Authors
Kim, SH; Sanak, M; Park, HS
Citation
Immunology and allergy clinics of North America, 33(2):177-194, 2013
Journal Title
Immunology and allergy clinics of North America
ISSN
0889-85611557-8607
Abstract
Various hypersensitivity reactions have been reported with aspirin and nonsteroidal anti-inflammatory drugs. Hypersensitivity can occur regardless of a chemical drug structure or its therapeutic potency. Allergic conditions include aspirin-exacerbated respiratory disease (AERD or aspirin-induced asthma), aspirin-induced urticaria/angioedema (AIU), and anaphylaxis. Several genetic studies on aspirin hypersensitivity have been performed to discover the genetic predisposition to aspirin hypersensitivity and to gain insight into the phenotypic diversity. This article updates data on the genetic mechanisms that govern AERD and AIU and summarizes recent findings on the molecular genetic mechanism of aspirin hypersensitivity.
MeSH terms
Anti-Inflammatory Agents, Non-Steroidal/*adverse effectsAspirin/*adverse effectsDrug Hypersensitivity/*genetics/immunologyHumans
DOI
10.1016/j.iac.2012.10.003
PMID
23639707
Appears in Collections:
Journal Papers > Research Organization > Regional Clinical Trial Center
Journal Papers > School of Medicine / Graduate School of Medicine > Allergy
AJOU Authors
김, 승현박, 해심
Full Text Link
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse