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A multi-institutional study on histopathological characteristics of surgically treated renal tumors: the importance of tumor size.
DC Field | Value | Language |
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dc.contributor.author | Kim, SI | - |
dc.contributor.author | Choi, YD | - |
dc.contributor.author | Kim, SJ | - |
dc.contributor.author | Chung, BH | - |
dc.contributor.author | Seong, DH | - |
dc.contributor.author | Kim, CI | - |
dc.contributor.author | Cheon, SH | - |
dc.contributor.author | Cho, JS | - |
dc.contributor.author | Song, YS | - |
dc.contributor.author | Kim, YS | - |
dc.contributor.author | Cho, IR | - |
dc.contributor.author | Lee, DH | - |
dc.contributor.author | Song, KH | - |
dc.contributor.author | Kim, HS | - |
dc.contributor.author | Lee, JS | - |
dc.contributor.author | Yang, WJ | - |
dc.contributor.author | Hong, SJ | - |
dc.date.accessioned | 2011-01-07T01:58:49Z | - |
dc.date.available | 2011-01-07T01:58:49Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | http://repository.ajou.ac.kr/handle/201003/1040 | - |
dc.description.abstract | PURPOSE: The incidence of accidentally detected small renal tumors is increasing throughout the world. In this multi-institutional study performed in Korea, histopathological characteristics of contemporarily surgically removed renal tumors were reviewed with emphasis on tumor size.
MATERIALS AND METHODS: Between January 1995 and May 2005, 1,702 patients with a mean age of 55 years underwent surgical treatment at 14 training hospitals in Korea for radiologically suspected malignant renal tumors. Clinicopathological factors and patient survival were analyzed. RESULTS: Of the 1,702 tumors, 91.7% were malignant and 8.3% were benign. The percentage of benign tumors was significantly greater among those < or = 4 cm (13.2%) than those > 4 cm (4.5%) (p < 0.001). Among renal cell carcinoma patients, the percentage of tumors classed as stage > or = T3 was significantly less among tumors < or = 4 cm (5.2%) than those > 4 cm (26.8%) (p < 0.001). The percentage of tumors classed as Fuhrman's nuclear grades > or = 3 was also significantly less among tumors < or = 4 cm (27.3%) than tumors > 4 cm (50.9%) (p < 0.001). The 5-year cancer-specific survival rate was 82.7%, and T stage (p < 0.001), N stage (p < 0.001), M stage (p = 0.025), and Fuhrman's nuclear (p < 0.001) grade were the only independent predictors of cancer-specific survival. CONCLUSION: In renal tumors, small tumor size is prognostic for favorable postsurgical histopathologies such as benign tumors, low T stages, and low Fuhrman's nuclear grades. Our observations are expected to facilitate urologists to adopt function-preserving approach in the planning of surgery for small renal tumors with favorable predicted outcomes. | - |
dc.language.iso | en | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Kidney Neoplasms | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.title | A multi-institutional study on histopathological characteristics of surgically treated renal tumors: the importance of tumor size. | - |
dc.type | Article | - |
dc.identifier.pmid | 18729308 | - |
dc.identifier.url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615292/ | - |
dc.contributor.affiliatedAuthor | 김, 선일 | - |
dc.contributor.affiliatedAuthor | 김, 세중 | - |
dc.type.local | Journal Papers | - |
dc.identifier.doi | 10.3349/ymj.2008.49.4.639 | - |
dc.citation.title | Yonsei medical journal | - |
dc.citation.volume | 49 | - |
dc.citation.number | 4 | - |
dc.citation.date | 2008 | - |
dc.citation.startPage | 639 | - |
dc.citation.endPage | 646 | - |
dc.identifier.bibliographicCitation | Yonsei medical journal, 49(4). : 639-646, 2008 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.relation.journalid | J005135796 | - |
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