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Topical 5-aminolaevulinic acid photodynamic therapy for intractable palmoplantar psoriasis.

Authors
Kim, JY; Kang, HY; Lee, ES; Kim, YC
Citation
The Journal of dermatology, 34(1):37-40, 2007
Journal Title
The Journal of dermatology
ISSN
0385-24071346-8138
Abstract
Photodynamic therapy (PDT) has been reported to be useful in treating non-melanoma skin cancers and a variety of benign skin conditions including psoriasis. However, only two reports of palmoplantar pustular psoriasis (PPP) treated with PDT have been reported. We treated three intractable cases of PPP with PDT, using 20% 5-aminolaevulinic acid and a 630+/-50 nm light-emitting diode device. The power density was 30 mW/cm2 and the fluence was 15 J/cm2. After treatment, all cases showed mild to marked improvement. Topical PDT may be an alternative therapy in the treatment of PPP, but further study is necessary to confirm the effectiveness of topical PDT in PPP.
MeSH terms
AdultAminolevulinic Acid/administration & dosage*Foot Dermatoses/drug therapyHand Dermatoses/drug therapyHumansMaleMiddle AgedPhotochemotherapy*Photosensitizing Agents/administration & dosage*Psoriasis/drug therapy*
DOI
10.1111/j.1346-8138.2007.00213.x
PMID
17204099
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Dermatology
AJOU Authors
강, 희영이, 은소김, 유찬
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