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Differential effect of side branch intervention on long-term clinical outcomes according to side branch stenosis after main vessel stenting: Results from the COBIS (Coronary Bifurcation Stenting) Registry II

Authors
Jang, WJ | Park, YH | Hahn, JY | Song, YB | Choi, SH | Chun, WJ | Hyeon Oh, J | Koo, BK | Rha, SW | Jang, Y | Tahk, SJ  | Kim, HS | Gwon, HC
Citation
International journal of cardiology, 221. : 471-477, 2016
Journal Title
International journal of cardiology
ISSN
0167-52731874-1754
Abstract
BACKGROUND: Indication of side branch (SB) intervention after main vessel (MV) stenting is not established for coronary bifurcation lesions. METHODS: We evaluated 2017 patients who were treated with 1-stent technique or MV stenting as a first strategy. Patients undergoing SB intervention after MV stenting (SB intervention group, n=929) were compared to those treated with MV stenting only (no-SB intervention group, n=1088). RESULTS: During a median follow-up of 37months, cardiac death or myocardial infarction (MI) tended to occur less frequently in the SB intervention group than in the no-SB intervention group (1.8% versus 2.9%: adjusted hazard ratio [HR] 0.53: 95% confidence interval [CI] 0.25-1.11: P=0.09). There was a significant interaction between SB intervention and SB stenosis after MV stenting (P for interaction <0.01). Among 1077 patients with diameter stenosis of SB >/=50% after MV stenting, SB intervention was associated with a lower risk of cardiac death or MI (1.2% versus 4.2%: adjusted HR 0.22: 95% CI 0.09-0.52: P<0.01). However, among 940 patients with diameter stenosis of SB <50%, there was no significant difference in cardiac death or MI between the SB intervention group and the no-SB intervention group (3.5% versus 2.2%: adjusted HR 1.36: 95% CI 0.58-3.20: P=0.48). CONCLUSIONS: The effect of SB intervention differed according to SB stenosis after MV stenting. SB intervention may reduce cardiac death or MI in bifurcation lesions with diameter stenosis of SB >/=50% after MV stenting.
MeSH

DOI
10.1016/j.ijcard.2016.07.045
PMID
27414725
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
Ajou Authors
탁, 승제
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