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Dysgerminoma of the ovary with precocious puberty: a case report.

Authors
Song, ES; Lee, JP; Han, JH; Kim, HY; Mun, SH; Ryu, HS; Chang, KH
Citation
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 23(1):34-37, 2007
Journal Title
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
ISSN
0951-35901473-0766
Abstract
Ovarian dysgerminoma is usually hormonally inert, but when it contains syncytiotrophoblastic giant cells or undergoes malignant transformation, the level of estradiol might be elevated. A 6-year-old girl contracted ovarian dysgerminoma with precocious puberty, and her levels of beta-human chorionic gondaotropin, alpha-fetoprotein and estradiol were high. After resection of the tumor, levels of tumor markers became normal and precocious puberty disappeared. We report this unusual type of dysgerminoma with a brief review of the literature.
MeSH terms
ChildDiagnosis, DifferentialDysgerminoma/diagnosis*Dysgerminoma/pathologyDysgerminoma/radiographyDysgerminoma/surgeryDysgerminoma/ultrasonographyFemaleHumansLaparotomyOvarian Neoplasms/diagnosis*Ovarian Neoplasms/pathologyOvarian Neoplasms/radiographyOvarian Neoplasms/surgeryOvarian Neoplasms/ultrasonographyPuberty, Precocious*Tomography, X-Ray Computed
PMID
17484510
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Obstetrics & Gynecology
Journal Papers > School of Medicine / Graduate School of Medicine > Pathology
Journal Papers > School of Medicine / Graduate School of Medicine > Medical Science
AJOU Authors
이, 정필한, 재호유, 희석장, 기홍
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