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Efficacy of different types of treatment in FIGO stage IB2 cervical cancer in Korea: results of a multicenter retrospective Korean study (KGOG-1005).

Authors
Ryu, HS; Kang, SB; Kim, KT; Chang, KH; Kim, JW; Kim, JH
Citation
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 17(1):132-136, 2007
Journal Title
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
ISSN
1048-891X1525-1438
Abstract
The purpose of this study is to review FIGO stage IB2 cervical cancers in Korea for the past 10 years, and evaluate the most frequently employed and appropriate management strategy, and also assess the survival benefits of neoadjuvant chemotherapy (NAC). This is a retrospective chart review of 727 FIGO stage IB2 patients from 1995 to 2005. Six hundred ninety-two patients were enrolled, and all dates on which the patients died were double checked through the "National Registry of Death Statistics" of the Korea National Statistical Office. Management strategies were divided into five groups according to the primary treatment modality. The most frequently employed primary treatment modality for stage IB2 cervical cancer in Korea during the past 10 years was radical hysterectomy (RH). The next was NAC, followed by radiotherapy (RT) and/or extrafascial hysterectomy, concurrent chemoradiotherapy (CCRT) and/or extrafascial hysterectomy, in descending order. The surgery group showed the best results, with an 89% 5-year disease-free survival rate. However, there was no statistical difference between the surgery, NAC, and CCRT groups. For FIGO stage IB2 cervical cancer during the past 10 years in Korea, RH and adjuvant RT or CCRT was the most frequently employed treatment strategy. As a primary modality, RH, NAC, and CCRT showed similar survival rates. However, RH demonstrated the best survival rate among the above treatment strategies.
MeSH terms
Age FactorsChemotherapy, AdjuvantFemaleHumansKoreaMiddle AgedNeoadjuvant TherapyNeoplasm StagingRadiotherapy, AdjuvantRetrospective StudiesUterine Cervical Neoplasms/pathology*Uterine Cervical Neoplasms/therapy*
DOI
10.1111/j.1525-1438.2007.00803.x
PMID
17291243
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Obstetrics & Gynecology
Journal Papers > School of Medicine / Graduate School of Medicine > Medical Science
AJOU Authors
유, 희석장, 기홍
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