Cited 25 times in

Useful Computed Tomography Score for Estimation of Early Neurologic Outcome in Post-Cardiac Arrest Patients With Therapeutic Hypothermia

Authors
Lee, KS | Lee, SE  | Choi, JY  | Gho, YR | Chae, MK  | Park, EJ  | Choi, MH  | Hong, JM
Citation
Circulation journal, 81(11). : 1628-1635, 2017
Journal Title
Circulation journal
ISSN
1346-98431347-4820
Abstract
BACKGROUND: The Alberta Stroke Program Early CT Score (ASPECTS) is used to assess early ischemic stroke damage. This study compared bilateral ASPECTS (ASPECTS-b) with the gray:white matter ratio (GWR) and quantitative regional abnormality (QRA) to evaluate the prognostic utility of early computed tomography (CT) findings in post-cardiac arrest patients.
Methods and Results:Out-of-hospital cardiac arrest patients with return of spontaneous circulation (ROSC) who underwent brain CT (<6 h after onset) and therapeutic hypothermia were recruited from a university hospital over a 2-year period. General demographics, ROSC characteristics, ASPECTS-b (total score=20 points), GWR, and QRA were assessed. Multivariate logistic regression analysis was used to predict neurologic outcome using cerebral performance category (CPC) at 1 month. The study population was divided into good (n=20: CPC 1-2) and poor (n=47: CPC 3-5) outcome groups. The good (vs. poor) outcome group was younger (mean [+/-SD] age 46.7+/-11.8 vs. 60.3+/-17.2 years: P=0.002) and had more initial shockable rhythms (40.0% vs. 8.5%: P=0.002). In addition, the good outcome group had a higher mean ASPECTS-b score (15.3+/-2.7 vs. 9.0+/-4.9: P<0.001), despite no differences in QRA and mean GWR. Age and ASPECTS-b were independent predictors of outcome after adjusting for potential confounders.
CONCLUSIONS: These findings suggest that an initial CT score (ASPECTS-b) could help estimate early neurologic outcomes in post-cardiac arrest patients treated with therapeutic hypothermia.
MeSH

DOI
10.1253/circj.CJ-16-1327
PMID
28592725
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Emergency Medicine
Journal Papers > School of Medicine / Graduate School of Medicine > Brain Science
Journal Papers > School of Medicine / Graduate School of Medicine > Neurology
Ajou Authors
박, 은정  |  이, 성은  |  최, 문희  |  최, 민정  |  최, 준영  |  홍, 지만
Files in This Item:
There are no files associated with this item.
Export

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse