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Development of Prediction Equation of Diffusing Capacity of Lung for Koreans

Hwang, YI | Park, YB | Yoon, HK | Lim, SY | Kim, TH | Park, JH  | Lee, WY | Park, SJ | Lee, SW | Kim, WJ | Kim, KU | Shin, KC | Kim, DJ | Kim, HJ | Kim, TE | Yoo, KH | Shim, JJ
Tuberculosis and respiratory diseases, 81(1). : 42-48, 2018
Journal Title
Tuberculosis and respiratory diseases
BACKGROUND: The diffusing capacity of the lung is influenced by multiple factors such as age, sex, height, weight, ethnicity and smoking status. Although a prediction equation for the diffusing capacity of Korea was proposed in the mid-1980s, this equation is not used currently. The aim of this study was to develop a new prediction equation for the diffusing capacity for Koreans.
METHODS: Using the data of the Korean National Health and Nutrition Examination Survey, a total of 140 nonsmokers with normal chest X-rays were enrolled in this study.
RESULTS: Using linear regression analysis, a new predicting equation for diffusing capacity was developed. For men, the following new equations were developed: carbon monoxide diffusing capacity (DLco)=-10.4433-0.1434xage (year)+0.2482xheights (cm): DLco/alveolar volume (VA)=6.01507-0.02374xage (year)-0.00233xheights (cm). For women the prediction equations were described as followed: DLco=-12.8895-0.0532xage (year)+0.2145xheights (cm) and DLco/VA=7.69516-0.02219xage (year)-0.01377xheights (cm). All equations were internally validated by k-fold cross validation method.
CONCLUSION: In this study, we developed new prediction equations for the diffusing capacity of the lungs of Koreans. A further study is needed to validate the new predicting equation for diffusing capacity.
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Journal Papers > School of Medicine / Graduate School of Medicine > Pulmonary & Critical Care Medicine
Ajou Authors
박, 주헌
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