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Molecular Epidemiology of Human Adenovirus-Associated Febrile Respiratory Illness in Soldiers, South Korea

Authors
Heo, JY  | Noh, JY | Jeong, HW | Choe, KW | Song, JY | Kim, WJ | Cheong, HJ
Citation
Emerging infectious diseases, 24(7). : 1221-1227, 2018
Journal Title
Emerging infectious diseases
ISSN
1080-60401080-6059
Abstract
During January 2013-April 2014, we subjected nasopharyngeal specimens collected from patients with acute febrile respiratory illness in a military hospital to PCR testing to detect 12 respiratory viruses and sequence a partial hexon gene for human adenovirus (HAdV) molecular typing. We analyzed the epidemiologic characteristics of HAdV infections and compared clinical characteristics of HAdV types. Among the 305 patients with acute febrile respiratory illness, we detected respiratory viruses in 139 (45.6%) patients: HAdV was the most prevalent virus (69 cases). Of the 40 adenoviruses identified based on type, HAdV-55 (29 cases) was the most prevalent, followed by HAdV-4 (9 cases). HAdV-55 was common in patients with pneumonia (odds ratio 2.17: 95% CI 0.48-9.86) and hospitalized patients (odds ratio 5.21: 95% CI 1.06-25.50). In soldiers with HAdV infection in Korea, HAdV-55 was the most prevalent type and might be associated with severe clinical outcomes.
MeSH

DOI
10.3201/eid2407.171222
PMID
29912713
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Infectious Diseases
Ajou Authors
허, 중연
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