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Cardiac 123I-MIBG scintigraphy in patients with essential tremor.

Authors
Lee, PH; Kim, JW; Bang, OY; Joo, IS; Yoon, SN; Huh, K
Citation
Movement disorders : official journal of the Movement Disorder Society, 21(8):1235-1238, 2006
Journal Title
Movement disorders : official journal of the Movement Disorder Society
ISSN
0885-31851531-8257
Abstract
In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using (123)I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor-dominant PD (TDPD). The mean ratio of (123)I-MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 +/- 0.21) than in those with either TDPD (1.28 +/- 0.11) or early PD (1.28 +/- 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD.
MeSH terms
3-Iodobenzylguanidine/diagnostic use*AgedAged, 80 and overDiagnosis, DifferentialEssential Tremor/physiopathology*Essential Tremor/radionuclide imaging*FemaleHeart/radionuclide imaging*Heart Diseases/epidemiologyHeart Diseases/radionuclide imagingHumansIodine Radioisotopes/diagnostic use*MaleMiddle AgedParkinson Disease/physiopathology*Parkinson Disease/radionuclide imaging*Radiopharmaceuticals/diagnostic use
DOI
10.1002/mds.20908
PMID
16671077
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Neurology
Journal Papers > School of Medicine / Graduate School of Medicine > Nuclear Medicine & Molecular Imaging
AJOU Authors
이, 필휴주, 인수윤, 석남허, 균
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