169 443

Cited 7 times in

Emphysema as a risk factor for the outcome of surgical resection of lung cancer.

Lee, SA; Sun, JS; Park, JH; Park, KJ; Lee, SS; Choi, H; Sheen, SS; Chung, WY; Lee, KS; Hwang, SC
Journal of Korean medical science, 25(8):1146-1151, 2010
Journal Title
Journal of Korean medical science
It is unclear whether emphysema, regardless of airflow limitation, is a predictive factor associated with survival after lung cancer resection. Therefore, we investigated whether emphysema was a risk factor associated with the outcome after resection for lung cancer. This study enrolled 237 patients with non small cell lung cancer with stage I or II who had surgical removal. Patient outcome was analyzed based on emphysema. Emphysema was found in 43.4% of all patients. Patients with emphysema were predominantly men and smokers, and had a lower body mass index than the patients without emphysema. The patients without emphysema (n=133) survived longer (mean 51.2+/-3.0 vs. 40.6+/-3.1 months, P=0.042) than those with emphysema (n=104). The univariate analysis showed a younger age, higher FEV(1)/FVC, higher body mass index, cancer stage I, and a lower emphysema score were significant predictors of better survival. The multivariate analysis revealed a younger age, higher body mass index, and cancer stage I were independent parameters associated with better survival, however, emphysema was not. This study suggests that unfavorable outcomes after surgical resection of lung cancer should not be attributed to emphysema itself.
MeSH terms
Age FactorsAgedBody Mass IndexCarcinoma, Non-Small-Cell Lung/complications/mortality/*surgeryEmphysema/*complicationsFemaleHumansLung Neoplasms/complications/mortality/*surgeryMaleMiddle AgedNeoplasm StagingPredictive Value of TestsRisk FactorsSmokingSurvival Rate
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Pulmonary & Critical Care Medicine
Journal Papers > School of Medicine / Graduate School of Medicine > Radiology
Journal Papers > School of Medicine / Graduate School of Medicine > Thoracic & Cardiovascular Surgery
Journal Papers > School of Medicine / Graduate School of Medicine > Medical Science
AJOU Authors
선, 주성박, 주헌박, 경주이, 성수최, 호신, 승수정, 우영이, 규성박, 광주황, 성철
Full Text Link
Files in This Item:
RIS (EndNote)
XLS (Excel)


해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.