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Conservative management of stage IA1 squamous cell carcinoma of the cervix with positive resection margins after conization.

Authors
Kim, WY; Chang, SJ; Chang, KH; Yoo, SC; Ryu, HS
Citation
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 109(2):110-112, 2010
Journal Title
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
ISSN
0020-72921879-3479
Abstract
OBJECTIVE: To evaluate the efficacy of cold knife conization with electrocauterization and the feasibility of conservative management in patients with stage IA1 carcinoma of the cervix according to margin status after conization.

METHODS: Medical and histopathological records of 108 patients with stage IA1 cervical carcinoma were reviewed retrospectively. Patients underwent cold knife conization with electrocauterization or conization followed by hysterectomy. Disease recurrence was defined as a histologic diagnosis of cervical intraepithelial neoplasia (CIN) 2 or higher grade lesion.

RESULTS: Forty patients underwent conization followed by hysterectomy; of 27 women with positive margins, 14 (35 positive endocervical (n=6).

CONCLUSION: Cold knife conization with electrocauterization appears to be a safe treatment option for patients with stage IA1 cervical carcinoma if careful follow-up is guaranteed for patients with CIN 3 exocervical resection margins. However, patients with CIN 3 endocervical resection margins should be managed surgically with repeat conization or hysterectomy.
MeSH terms
AdultCervical Intraepithelial Neoplasia/pathology/*surgeryConization/*methodsElectrocoagulation/*methodsFemaleHumansHysterectomyMiddle AgedNeoplasm Recurrence, Local/diagnosis/pathologyNeoplasm StagingNeoplasms, Squamous Cell/pathology/*surgeryRetrospective StudiesUterine Cervical Neoplasms/pathology/*surgery
DOI
10.1016/j.ijgo.2009.11.017
PMID
20096835
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Medical Science
Journal Papers > School of Medicine / Graduate School of Medicine > Obstetrics & Gynecology
AJOU Authors
김, 우영장, 석준장, 기홍유, 승철유, 희석
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