150 238

Cited 13 times in

Clinical and histopathological characteristics of pityriasis alba.

Authors
In, SI; Yi, SW; Kang, HY; Lee, ES; Sohn, S; Kim, YC
Citation
Clinical and experimental dermatology, 34(5):591-597, 2009
Journal Title
Clinical and experimental dermatology
ISSN
0307-69381365-2230
Abstract
BACKGROUND: Pityriasis alba (PA) is a skin disorder characterized by asymptomatic, variably hypopigmented, slightly scaling patches with indistinct margins. It is sometimes difficult to clinically differentiate PA from other hypopigmented disorders such as naevus depigmentosus. AIM: To examine the clinical and histopathological characteristics of PA that are important in differentiating PA from other hypopigmenting disorders. METHODS: A clinical survey was carried out on 56 patients with PA. Histopathological features were investigated with immunostains for NKI/beteb antibody, melanoma antigen recognized by T cells (MART)-1 and S-100 protein, and by haematoxylin and eosin and Fontana-Masson stains. RESULTS: Of the 56 PA patients, 10 (18%) had a previous history of atopic dermatitis and 9 (16%) had a solitary lesion. Histopathological study revealed markedly reduced pigment in the epidermis of lesional skin, but no significant difference in melanocyte count was found between lesional and normal skin. Ultrastructurally, degenerative changes in melanocytes and a reduced number of melanosomes within keratinocytes were seen. CONCLUSION: No significant difference in the number of melanocytes between lesional and normal skin was seen. These findings should be considered when diagnosing and differentiating PA from other hypopigmentary disorders.
MeSH terms
AdolescentChildChild, PreschoolDiagnosis, DifferentialFacial Dermatoses/pathologyHumansHypopigmentation/diagnosis*Hypopigmentation/pathologyImage Processing, Computer-Assisted/methodsKeratinocytes/ultrastructureMelanins/analysisMelanocytes/ultrastructureMicroscopy, ElectronPityriasis/diagnosis*Pityriasis/pathologyRetrospective StudiesSkin/ultrastructure
DOI
10.1111/j.1365-2230.2008.03038.x
PMID
19094127
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Dermatology
Journal Papers > School of Medicine / Graduate School of Medicine > Microbiology
AJOU Authors
강희영이은소손성향김유찬
Full Text Link
Files in This Item:
Full-Text Not Available.txtDownload
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse