77 145

Cited 0 times in

Clinical Implication of Prostaglandin E2 Content in Lumbar Disc Disease

Other Title
추간판내 Prostaglandin E2 양의 임상적 의의
Authors
김, 형석; 조, 기홍; 김, 기용; 안, 영환; 안, 영민; 윤, 수한; 조, 경기
Citation
Taehan Sinkyŏng Oekwa Hakhoe chi, 29(10):1340-1344, 2000
Journal Title
Taehan Sinkyŏng Oekwa Hakhoe chi; Journal of Korean Neurosurgical Society; 대한신경외과학회지
ISSN
1225-8245
Abstract
Objective:A prospective biochemical assay of prostaglandin E2 content in symptomatic lumbar disc materials was done in order to clarify the pathogenesis of lumbar radiculopathy.



Patients and Methods:Forty-eight disc specimens were purified by a standard solid-phase extraction procedure and analyzed by an enzymelinked immunosorbent assay for prostaglandin E2. Clinical and anatomic correlations were evaluated with analysis of variance and t-test.



Results:Acute herniated lumbar disc diseases tended to be associated with a higher prostaglandin E2 content than degenerative lumbar disc disease. Sequestered discs tended to be associated with a higher prostaglandin E2 content than extruded discs, which also showed higher prostaglandin E2 content than protruded ones. A sciatica and positive straight leg raising test appeared to be associated with a higher prostaglandin E2 content than a negative test.



Conclusion:This result suggests that the level of prostaglandin E2 would be correlated with clinical symptom and sign in the inflammatory process of lumbar disc herniation.
Keywords
Intervertebral disc herniationRadiculopathyProstaglandin E2
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Neurosurgery
Full Text Link
Files in This Item:
0042000195.pdfDownload
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse