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Impaired Glucose Tolerance Associated with Klinefelter Syndrome -A case with peripheral insulin resistance clarified by euglycemic hyperinsulinemic clamp test

Other Title
내당능장애를 동반한 Klinefelter 증후군 1예 -정상혈당클램프검사로 인슬린 저항성을 확인한 예-
Authors
차, 충근; 엄, 철; 김, 윤정; 권, 오영; 채, 봉남; 홍, 은경; 이, 성규; 정, 윤석; 이, 관우
Citation
Journal of Korean Society of Endocrinology, 13(3):495-500, 1998
Journal Title
Journal of Korean Society of Endocrinology; 대한내분비학회지
ISSN
1015-6380
Abstract
Klinefelter syndrome is one of the most common forms of primary hypogonadism and

infertility in males. It is a clinical syndrome consisting of gynecomastia, azoospermia,

and increased urinary excretion of follicle-stimulating hormone. Frequency of diabetes

mellitus, emphysema, asthma, breast cancer increase in Klinefelter syndrome. We report

a 16-year-old male patient with impaired glucose tolerance in association with

Klinefelter syndrome, which was confirmed by chromosome analysis. The mechanism of

impaired glucose tolerance in this patient was peripheral insulin resistance which

clarified by euglycomic hyperinsulinemic clamp test.
Keywords
Klinefelter syndromeImpaired glucose toleranceEuglycemic hyperinsulinemic clamp test
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Endocrinology & Metabolism
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