Cytokeratin Expressions of Induced Cholesteatoma in Gerbil
실험적 진주종의 사이토케라틴 발현양상
박, 기현; 전, 영명; 박, 홍준
Taehan Ibi Inhukwa Hakhoe chi, 39(5):747-753, 1996
Taehan Ibi Inhukwa Hakhoe chi; Journal of the Korean Otolaryngological Society; 대한이비인후과학회지
Cholesteatoma is characterized by the presence of a keratinizing epithelium in the middle ear. The accumulation of desquamous epithelial cells appears to be a crucial factor in the pathogenesis of the middle ear chlesteatoma. The accumulation of
keratin debris is due to the migration, proliferation, and differentiation of basal keratinocytes.
In the present study, we investigated the expression of specific cytokeratins in the experimental cholesteatoma in gerbil to determine whether any difference of differentiation and proliferation between cholesteatoma and normal skin using several
Cytokeratin expression patterns of induced cholesteatoma and deep meatal skin were characterized ty the presence of hyperproliferative charateristics and some atypical variations. These suggest that extensive accumulation of keratinous mass in
meatus may changes in cellualr differentiation and proliferation.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
Total Visit :5,300,017
Total Download :2,239,589
Today View :2,468
Ajou University Medical Information & Media Center 164 Worldcup-ro Yeongtong-gu Suwon 16499 Korea / TEL : 031-219-5312 / FAX : 031-219-5314 Copyright (c) Ajou University Medical Information & Media Center All Rights Reserved. AJOU Open Repository는 국립중앙도서관 OAK 보급사업으로 구축되었습니다.