42 129

Cited 0 times in

Cytokeratin Expressions of Induced Cholesteatoma in Gerbil

Other Title
실험적 진주종의 사이토케라틴 발현양상
Authors
박, 기현; 전, 영명; 박, 홍준
Citation
Taehan Ibi Inhukwa Hakhoe chi, 39(5):747-753, 1996
Journal Title
Taehan Ibi Inhukwa Hakhoe chi; Journal of the Korean Otolaryngological Society; 대한이비인후과학회지
ISSN
1225-035X
Abstract
Cholesteatoma is characterized by the presence of a keratinizing epithelium in the middle ear. The accumulation of desquamous epithelial cells appears to be a crucial factor in the pathogenesis of the middle ear chlesteatoma. The accumulation of

the

keratin debris is due to the migration, proliferation, and differentiation of basal keratinocytes.

In the present study, we investigated the expression of specific cytokeratins in the experimental cholesteatoma in gerbil to determine whether any difference of differentiation and proliferation between cholesteatoma and normal skin using several

specific cytokeratin.

Cytokeratin expression patterns of induced cholesteatoma and deep meatal skin were characterized ty the presence of hyperproliferative charateristics and some atypical variations. These suggest that extensive accumulation of keratinous mass in

external

meatus may changes in cellualr differentiation and proliferation.
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Otolaryngology
Files in This Item:
Full-Text Not Available.txtDownload
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse